Table 3

Maternal grandmaternal smoking during pregnancy and FEV₁/FVC % predicted. Stratified by gender and maternal smoking during pregnancy. Adjusted for gender, maternal smoking, current or former smoking, passive environmental smoke exposure in childhood, maternal age, birth weight, gestational age, breast feeding and socioeconomic status

	Children (<18 years)		Adults (≥18 years)
	Beta-coefficient (95% CI)	P value	Beta-coefficient (95% CI)	P value
Total	n=6216		n=14 752
Unadjusted	−0.32 (−0.75 to 0.1)	0.136	−0.3 (−0.79 to 0.2)	0.238
Adjusted	−0.15 (−0.57 to 0.28)	0.503	−0.19 (−0.68 to 0.30)	0.445
Females	n=3376		n=9163
Unadjusted	−0.43 (−0.98 to 0.12)	0.123	0.20 (−0.39 to 0.79)	0.510
Adjusted	−0.23 (−0.78 to 0.32)	0.412	0.31 (−0.29 to 0.90)	0.311
Males	n=2840		n=5589
Unadjusted	−0.18 (−0.84 to 0.49)	0.599	−1.15 (−2.02 to −0.28)	0.010
Adjusted	−0.06 (−0.73 to 0.60)	0.852	−1.04 (−1.91 to −0.16))	0.020
Non-smoking mother	n=5030		n=10 505
Unadjusted	−0.29 (−0.78 to 0.20)	0.243	0.33 (−0.31 to 0.98)	0.308
Adjusted	−0.25 (−0.74 to 0.23)	0.308	0.25 (−0.39 to 0.89)	0.443
Smoking mother	n=710		n=2736
Unadjusted	0.09 (−0.99 to 1.18)	0.867	−0.80 (−1.69 to 0.09)	0.077
Adjusted	0.03 (−1.07 to 1.13)	0.960	−0.91 (−1.81 to −0.01))	0.047