Demographics for the study population at baseline
| All participants | AChE/Hb <26.3 U/g | AChE/Hb ≥26.3 U/g | |
| Total, n | 364 | 181 | 183 |
| Sex | |||
| Female, n (%) | 250 (68.7) | 132 (72.9) | 118 (64.5) |
| Male, n (%) | 114 (31.3) | 49 (27.1) | 65 (35.5) |
| Age, years | 46.6 (36.7 to 56.5) | 46.8 (37.0 to 56.5) | 46.5 (36.6 to 56.5) |
| Years of full-time education | 7.0 (5.0 to 11.0) | 7.0 (5.0 to 10.0) | 7.0 (5.0 to 11.0) |
| Ethnicity | |||
| Baganda, n (%) | 283 (77.7) | 137 (75.7) | 146 (79.8) |
| Banyarwanda, n (%) | 20 (5.5) | 15 (8.3) | 5 (2.7) |
| Banyankore, n (%) | 11 (3.0) | 5 (2.8) | 6 (3.3) |
| Other, n (%) | 50 (13.7) | 24 (13.3) | 26 (14.2) |
| Ever smoked tobacco? | |||
| Yes, n (%) | 42 (11.5) | 17 (9.4) | 25 (13.7) |
| No, n (%) | 322 (88.5) | 164 (90.6) | 158 (86.3) |
| Current smoker? | |||
| Yes, n (%) | 15 (4.1) | 4 (2.2) | 11 (6.0) |
| No, n (%) | 349 (95.9) | 177 (97.8) | 172 (94.0) |
| Pack-years (ever-smokers only) | 2.1 (0.9 to 6.8) | 4.0 (1.2 to 8.4) | 1.8 (0.8 to 6.2) |
| Grams of tobacco per day for current smokers | 1.1 (0.0 to 4.0) | 1.9 (0.4 to 6.0) | 1.1 (0.0 to 4.0) |
| Cooking fuel type in household | |||
| Charcoal, n (%) | 61 (16.8) | 37 (20.4) | 24 (13.1) |
| Wood, n (%) | 298 (81.9) | 142 (78.5) | 156 (85.2) |
| No food cooked in household, n (%) | 1 (0.3) | 0 (0.0) | 1 (0.5) |
| Other, n (%) | 4 (1.1) | 2 (1.1) | 2 (1.1) |
| Number of hours of cooking in the last week | 8.0 (0.3 to 17.8) | 8.0 (0.5 to 16.7) | 8.0 (0.0 to 20.0) |
| Cumulated lifetime cooking (‘cooking years’) | 16.7 (0.9 to 44.9) | 14.9 (1.2 to 44.7) | 17.5 (0.0 to 45.2) |
| BMI, kg/m2 | 23.3 (21.1 to 26.8) | 23.2 (21.1 to 26.9) | 23.3 (21.5 to 26.5) |
| Mean height across all phases, cm | 158.9 (154.1 to 164.3) | 158.5 (152.7 to 163.2) | 159.5 (155.0 to 164.7) |
| Ever mixed or applied pesticides?* | |||
| Yes, n (%) | 283 (77.8) | 140 (77.3) | 143 (78.1) |
| No, n (%) | 81 (22.3) | 41 (22.7) | 40 (21.9) |
| Cholinesterase inhibitor insecticides among three most used pesticides, or used in the last week?† | |||
| Yes, n (%) | 133 (47.0) | 64 (45.7) | 69 (48.3) |
| No, n (%) | 114 (40.3) | 53 (37.9) | 61 (42.7) |
| Unknown, n (%) | 36 (12.7) | 23 (16.4) | 13 (9.1) |
| Cholinesterase inhibitor insecticides used in the last week?† | |||
| Yes, n (%) | 22 (7.8) | 9 (6.4) | 13 (9.1) |
| No, n (%) | 246 (86.9) | 120 (85.7) | 126 (88.1) |
| Unknown, n (%) | 15 (5.3) | 11 (7.9) | 4 (2.8) |
Categorical variables are n (%). Continuous variables are median (IQR). AChE/Hb dichotomised by 26.3 U/g, the median AChE/Hb at baseline. One ‘cooking year’ is defined as cooking for 2.5 hours per day for 365.24 days.
*Includes both occupational and domestic use of pesticides.
†Data only presented for subjects who have ever mixed or applied pesticides.
AChE/Hb, erythrocyte acetylcholinesterase normalised by haemoglobin concentration; BMI, body mass index.