Findings stratified by NSBHR test result (data are presented as n(%) unless otherwise stated. P-values are calculated excluding the ‘not recorded’ data)
| All n=120 | NSBHR+ (PC20 <8 mg/ml) n=19 | NSBHR- (PC20 ≥8 mg/ml) n=101 | P-value | |
|---|---|---|---|---|
| Male | 105 (87.5) | 16 (84.2) | 89 (88.1) | 0.705 |
| Age, median (range) | 26 (23–31) | 29 (22–35) | 26 (23–31) | 0.375 |
|
Smoking
Current Ever Never Not recorded | 9 (7.5) 24 (20.0) 81 (67.5) 6 (5.0) | 0 (0.0) 5 (26.3) 14 (73.7) 0 (0.0) | 9 (8.9) 19 (18.8) 62 (66.3) 6 (5.9) | 0.334 |
|
Atopic to common aeroallergens
Yes No Not recorded | 87 (72.5) 19 (15.8) 14 (11.7) | 18 (94.7) 0 (0.0) 1 (5.3) | 69 (68.3) 19 (18.8) 13 (12.9) | 0.038 |
|
Self-reported atopic disease
Yes No Not recorded | 74 (61.7) 23 (19.2) 23 (19.2) | 17 (89.5) 1 (5.3) 1 (5.3) | 57 (56.4) 22 (21.8) 22 (21.8) | 0.063 |
|
Adult symptoms/
treatment
Yes No Not recorded | 84 (70.0) 34 (28.3) 2 (1.7) | 15 (79.0) 4 (21.1) 0 (0) | 69 (68.3) 30 (29.7) 2 (2.0) | 0.590 |
|
Last treatment as an adult (any)
Never > 1 year ago <1 year ago Not recorded | 47 (39.2) 25 (20.8) 42 (35.0) 6 (5.0) | 4 (21.1) 3 (15.8) 11 (57.9) 1 (5.3) | 43 (42.6) 22 (21.8) 31 (30.7) 5 (5.0) | 0.062 |
| Childhood asthma (treatment and/or diagnosis) | 100 (83.3) | 14 (73.7) | 86 (85.2) | 0.219 |
| FEV1%predicted; mean (sd) | 101.09 (12.5) | 93.1 (15.5) | 102.6 (11.3) | 0.002 |
| FVC% predicted; mean (sd) | 110.8 (12.0) | 106.6 (15.2) | 111.7 (11.2) | 0.090 |
| FEV1/FVC, mean (sd) | 0.78 (0.09) | 0.74 (0.06) | 0.79 (0.09) | 0.023 |