Table 3

Flow volume spirometry data

Patients (n=48)Volunteers (n=11)P value
FVC
% predicted86.5 (80.5–100.0)97.0 (91.0–110.0)0.02*
z-score−1.0±1.30.1±1.10.02*
FEV1
% predicted80.5 (73.0–91.0)97.0 (91.0–107.0)0.001*
z-score−1.6 (−2.3 to −0.8)−0.3 (−0.8 to 0.6)0.001*
FEV1/FVC
% predicted91.0 (79.3–96.0)100 (94.0–106.0)0.02*
z-score−1.4±1.6−0.3±1.60.04*
PEF
% predicted58.5 (41.3–71.8)111.0 (78.0–123.0)<0.001*
z-score−3.1 (−4.4 to −2.2)0.6 (−1.6 to 1.6)<0.001*
FEF25
% predicted61.5 (43.5–61.5)109.0 (76.0–127.0)<0.001*
z-score−2.8±1.4−0.3±2.2<0.001*
FEF50
% predicted62.1±21.893.1±44.8<0.001*
z-score−2.4±1.5−0.8±2.30.007*
FEF75
% predicted81.5±36.2104.4±44.80.08
z-score−0.8±1.4−0.1±1.40.11
MEF
% predicted64.0±23.092.8±31.70.001*
z-score−1.8±1.3−0.4±1.50.003*
VCmax
% predicted89.1±15.2100.7±12.70.02*
z-score−1.1 (−1.53–0.0)−0.3 (−0.8–0.9)0.02*
FVC in
% predicted75.5±15.085.7±15.40.05*
FIV1 (L)1.7 (1.3–2.5)2.7 (1.6–5.6)0.47
FIV1/FVC in (%)78.5 (65.0–92.1)99.8 (88.2–100.0)0.01*
FIV1/VCmax (%)66.3±16.580.9±9.50.007*
FEV1/FIV1 (%)119.0±25.8105.3±17.60.1
EDI (%)62.6 (52.5–79.4)45.3 (43.9–50.1)0.001*
  • Spirometry data. Data are presented as mean±SD or median (IQR).

  • *P<0.05.

  • EDI, Expiratory Disproportion Index; FEF25-75, forced expiratory flow at 25%–75% of expiration; FEV1, forced expiratory volume in 1 s; FIV1, forced inspiratory volume in 1 s; FIV in, forced inspiratory volume; FVC, forced vital capacity; FVC in, forced vital capacity inspiratory; MEF, mean expiratory flow; PEF, peak expiratory flow; VC max, maximum vital capacity.