Table 3

Flow volume spirometry data

	Patients (n=48)	Volunteers (n=11)	P value
FVC
% predicted	86.5 (80.5–100.0)	97.0 (91.0–110.0)	0.02*
z-score	−1.0±1.3	0.1±1.1	0.02*
FEV₁
% predicted	80.5 (73.0–91.0)	97.0 (91.0–107.0)	0.001*
z-score	−1.6 (−2.3 to −0.8)	−0.3 (−0.8 to 0.6)	0.001*
FEV₁/FVC
% predicted	91.0 (79.3–96.0)	100 (94.0–106.0)	0.02*
z-score	−1.4±1.6	−0.3±1.6	0.04*
PEF
% predicted	58.5 (41.3–71.8)	111.0 (78.0–123.0)	<0.001*
z-score	−3.1 (−4.4 to −2.2)	0.6 (−1.6 to 1.6)	<0.001*
FEF25
% predicted	61.5 (43.5–61.5)	109.0 (76.0–127.0)	<0.001*
z-score	−2.8±1.4	−0.3±2.2	<0.001*
FEF50
% predicted	62.1±21.8	93.1±44.8	<0.001*
z-score	−2.4±1.5	−0.8±2.3	0.007*
FEF75
% predicted	81.5±36.2	104.4±44.8	0.08
z-score	−0.8±1.4	−0.1±1.4	0.11
MEF
% predicted	64.0±23.0	92.8±31.7	0.001*
z-score	−1.8±1.3	−0.4±1.5	0.003*
VCmax
% predicted	89.1±15.2	100.7±12.7	0.02*
z-score	−1.1 (−1.53–0.0)	−0.3 (−0.8–0.9)	0.02*
FVC in
% predicted	75.5±15.0	85.7±15.4	0.05*
FIV₁ (L)	1.7 (1.3–2.5)	2.7 (1.6–5.6)	0.47
FIV₁/FVC in (%)	78.5 (65.0–92.1)	99.8 (88.2–100.0)	0.01*
FIV₁/VCmax (%)	66.3±16.5	80.9±9.5	0.007*
FEV₁/FIV₁ (%)	119.0±25.8	105.3±17.6	0.1
EDI (%)	62.6 (52.5–79.4)	45.3 (43.9–50.1)	0.001*

Spirometry data. Data are presented as mean±SD or median (IQR).
*P<0.05.
EDI, Expiratory Disproportion Index; FEF_25-75, forced expiratory flow at 25%–75% of expiration; FEV₁, forced expiratory volume in 1 s; FIV₁, forced inspiratory volume in 1 s; FIV in, forced inspiratory volume; FVC, forced vital capacity; FVC in, forced vital capacity inspiratory; MEF, mean expiratory flow; PEF, peak expiratory flow; VC max, maximum vital capacity.