Differences in mean scores on psychological outcomes between the screening and community comparison sample by type of LDCT result
| Community sample (ref) | LSUT sample by screening result | |||||||
| Negative LDCT scan | Indeterminate pulmonary nodule | Suspicious thoracic lesion | Incidental finding GP follow-up | Incidental finding hospital follow-up | No LDCT scan | P value | ||
| Cancer worry T0, mean (95% CI) | 9.32 (8.96 to 9.69) | 11.81** (11.27 to 12.35) | 11.04** (10.36 to 11.71) | 12.11* (10.71 to 13.51) | 11.25** (10.86 to 11.65) | 10.86 (9.80 to 11.93) | 11.06** (10.45 to 11.68) | <0.001 |
| Cancer worry T1, mean (95% CI) | 11.37** (10.77 to 11.98) | 11.00* (10.28 to 11.72) | 11.42 (9.58 to 13.26) | 10.84** (10.31 to 11.38) | 11.20 (9.35 to 13.05) | 10.14 (9.32 to 10.96) | <0.001 | |
| Cancer worry T2, mean (95% CI) | 11.24** (10.59 to 11.89) | 12.97** (11.96 to 13.98) | 12.95* (11.03 to 14.87) | 11.52** (10.92 to 12.12) | 13.05* (10.80 to 15.30) | 12.03** (10.70 to 13.36) | <0.001 | |
| Anxiety T0, mean (95% CI) | 3.32 (2.94 to 3.70) | 5.25** (4.54 to 5.96) | 4.37 (3.56 to 5.19) | 5.17 (3.79 to 6.56) | 4.49* (3.97 to 5.01) | 3.47 (2.31 to 4.63) | 4.96* (4.24 to 5.68) | <0.001 |
| Anxiety T2, mean (95% CI) | 5.29** (4.38 to 6.21) | 6.93** (5.65 to 8.21) | 6.39 (4.04 to 8.74) | 5.34** (4.67 to 6.02) | 4.94 (2.93 to 6.95) | 6.51** (5.25 to 7.77) | <0.001 | |
| Depression T0, mean (95% CI) | 3.85 (3.44 to 4.27) | 3.58 (3.04 to 4.12) | 3.21 (2.51 to 3.91) | 3.89 (2.42 to 5.36) | 3.28 (2.85 to 3.72) | 2.65 (1.63 to 3.66) | 3.15 (2.58 to 3.73) | 0.23 |
| Depression T2, mean (95% CI) | 3.25 (2.49 to 4.02) | 4.81 (3.67 to 5.96) | 5.28 (2.71 to 7.84) | 3.93 (3.35 to 4.51) | 3.33 (1.73 to 4.93) | 5.38 (4.25 to 6.51) | 0.01 | |
Score ranges for each psychological outcome measure are: cancer worry (7–29), anxiety (0–21), depression (0–21).
*p<0.01 for Tukey HSD posthoc test, **p<0.001 for Tukey HSD posthoc test.
GP, General Practitioner; HSD, honest significant difference; LDCT, low-dose CT.