Table 2

Demographic and clinical characteristics of patients with HS and IPF enrolled in plasma-exosomal microRNA study (cohort 2)

Cohort 2HS
(n=14)
IPF
(n=14)
P value
Demographic characteristics
 Age (years)62±371±90.1057
 Gender (M/F)5/912/2 0.0183
 BMI (kg/m²)26±5,3428±50.2703
 Smokers (NS/FS/S)4/8/21/13/00.0825
Functional characteristics and therapy
 FEV1 post-BD, %pred.107±2176±14 0.0000
 FVC post-BD, %pred.113±2477±16 0.0000
 FEV1/FVC post-BD, %pred.77±3,7876±110.7384
 TLC, %pred.75±21
 DLCO, %pred.41±16
 KCO, %pred.64±22
 Immunosuppressor: yes (%)33
 OCS: yes (%)38
  • Data are presented as mean±SD or median (IQR).

  • *P value in bold indicate statistically significant differences between groups

  • BD, bronchodilator test; BMI, body mass index; DLCO, diffusing capacity of the lung for carbon monoxide; F, female; FEV1, forced expiratory volume in one second; FS, former smoker; FVC, forced vital capacity; HS, healthy subject; IPF, idiopathic pulmonary fibrosis; KCO, transfer coefficient; M, male; NS, non-smoker; OC, oral corticosteroid; %pred., per cent predicted; S, smoker; TLC, total lung capacity.