Table 1

Participant characteristics by group (% totals may not sum up due to rounding or missing data)

VariablesNo LDCT n=228
median (IQR) or n (%)
No lung cancer n=732
median (IQR) or n (%)
Lung cancers n=36
median (IQR) or n (%)
All groups n=996
median (IQR) or n (%)
Age (in years)
60–6386 (37.7)241 (32.9)8 (22.2)335 (33.6)
64–6772 (31.6)238 (32.5)11 (30.6)321 (32.2)
68–7248 (21.1)158 (21.6)13 (36.1)219 (22.0)
73–7622 (9.7)95 (13.0)4 (11.1)121 (12.2)
Gender
Female109 (47.8)317 (43.3)23 (63.9)449 (45.1)
Ethnicity
White183 (80.3)607 (82.9)34 (94.4)824 (82.7)
Black/African/Caribbean23 (10.1)77 (10.5)1 (2.8)101 (10.1)
Other22 (9.7)48 (6.6)1 (2.8)71 (7.1)
Highest level of education
Left school at or before age 15105 (46.1)395 (54.0)20 (55.6)520 (52.2)
GCSEs, O-levels or equivalent26 (11.4)75 (10.3)3 (8.3)104 10.4)
A-levels or equivalent24 (10.5)70 (9.6)4 (11.1)98 (9.8)
Further education14 (6.1)31 (4.2)3 (8.3)48 (4.8)
Bachelor degree34 (14.9)84 (11.5)2 (5.6)120 (12.1)
Further higher degree20 (8.8)64 (8.7)4 (11.1)88 (8.8)
Other5 (2.2)13 (1.8)0 (0)18 (1.8)
Index of Multiple Deprivation quintile
1 (most deprived)117 (51.3)402 (54.9)19 (52.8)538 (54.0)
287 (38.2)245 (33.5)12 (33.3)344 (34.5)
33 (1.3)17 (2.3)1 (2.8)21 (2.1)
40 (0)2 (0.3)0 (0)2 (0.2)
5 (least deprived)0 (0)0 (0)0 (0)0 (0)
Smoking history
Current smoker148 (64.9)527 (72.0)31 (86.1)706 (70.9)
Years smoked (years)42 (33 to 51)47 (44 to 51)51 (47 to 54)47 (42 to 51)
Years quit (years)0 (0 to 3)0 (0 to 0)0 (0 to 0)0 (0 to 0)
Average smoking intensity (cigs/day)14 (8 to 20)20 (10 to 20)20 (10 to 23)17 (10 to 20)
Pack years23 (10 to 41)38 (26 to 51)46 (26 to 63)36 (21 to 50)
Lung cancer risk
PLCO (% 6-year risk)1.40 (0.39 to 5.48)3.74 (1.80 to 7.14)5.68 (2.96 to 9.27)3.43 (1.38 to 6.97)
LLP (% 5-year risk)3.07 (1.55 to 7.16)5.58 (3.79 to 8.75)5.5 (4.58 to 9.77)5.20 (3.16 to 8.56)
Physical measurements
FEV1 (l/min)2.12 (1.68 to 2.57)2.06 (1.64 to 2.56)1.74 (1.12 to 2.2)2.06 (1.64 to 2.55)
FEV1 (% predicted)85 (69 to 98)82 (66 to 96)73 (53 to 89)82 (67 to 97)
FEV/FVC (%)70 (63 to 77)69 (61 to 75)62 (54 to 69)69 (62 to 76)
BMI (kg/m2)25.8 (22.9 to 29.1)26.2 (23 to 29.4)23.5 (22.5 to 26)26.0 (22.9 to 29.2)
WHO Performance Status
0 - asymptomatic203 (89.0)660 (90.2)28 (77.8)891 (89.5)
1 - completely ambulatory23 (10.1)64 (8.7)8 (22.2)95 (9.5)
2 - <50% of day in chair/ bed1 (0.4)8 (1.1)0 (0)9 (0.9)
3 - >50% of day in chair/ bed1 (0.4)0 (0)0 (0)1 (0.1)
LDCT
Follow-up duration since LDCT (days)n/a1007 (851 to 1143)1044 (933 to 1153)1008 (853 to 1144)
  • BMI, body mass index; cigs, cigarettes; CT, Computed Tomography scan; GCSE, General Certificate of Secondary Education; LDCT, low-dose CT; LLP, Liverpool Lung Project; PLCO, Prostate, Lung, Colorectal and Ovarian study; USPSTF, United States Preventive Services Task Force; VATS, Video Assisted Thoracoscopic Surgery.