Table 1

Comparison of cases and controls for environmental exposures and family history: ORs, 95% CIs and p values

Environmental exposures	Cases (n=503)			Controls (n=902)			Unadjusted ORs	Adjusted ORs
	Total	Exposed		Total	Exposed			OR	95% CI	P value
	Total	n	%	Total	n	%		OR	95% CI	P value
Smoking
Tobacco (ever)	501	352	70.3	902	475	52.7	2.12	2.20*	(1.74 to 2.79)	<0.001
Past tobacco	501	340	67.9	902	412	45.7	2.51	2.61*	(2.06 to 3.29)	<0.001
Current tobacco	501	12	2.4	902	63	7.0	0.33	0.33*	(0.17 to 0.62)	0.001
Secondhand smoke	498	377	75.7	902	663	73.5	1.12	1.03	(0.79 to 1.33)	0.856
Pipe	498	89	17.9	902	137	15.2	1.22	1.05	(0.76 to 1.45)	0.752
Marijuana	497	34	6.8	902	101	11.2	0.58	0.51	(0.33 to 0.78)	0.002
Self-assessed exposures
Asbestos	484	194	40.1	902	304	33.7	1.32	1.37	(1.08 to 1.74)	0.009
Silica	480	64	13.3	902	176	19.5	0.63	0.61	(0.44 to 0.84)	0.003
Gases/fumes/chemicals	494	242	49.0	902	424	47.0	1.08	1.09	(0.86 to 1.38)	0.465
Dusty environment	499	260	52.1	902	456	50.6	1.06	1.07	(0.85 to 1.36)	0.546
Family history
Pulmonary fibrosis	490	63	12.9	902	11	1.2	12.0	12.6	(6.52 to 24.2)	<0.001
Autoimmune disease	489	67	13.7	902	113	12.5	1.11	1.12	(0.81 to 1.56)	0.490
Home exposures
Indoor hot tub	499	15	3.0	902	26	2.9	1.04	1.00	(0.52 to 1.93)	0.994
Water leaks/mould	496	45	9.1	902	90	10.0	0.90	0.91	(0.61 to 1.32)	0.597
Down pillows/doonas	488	178	36.5	902	293	32.5	1.19	1.20	(0.94 to 1.52)	0.138
Pigeons/parakeet/birds	496	43	8.7	902	131	14.5	0.56	0.54	(0.37 to 0.78)	0.001
House/office damp	496	22	4.4	902	38	4.2	1.06	1.07	(0.62 to 1.85)	0.800
Flooding history	499	11	2.2	902	33	3.7	0.59	0.56	(0.28 to 1.13)	0.106
Standing water	498	32	6.4	902	109	12.1	0.50	0.51	(0.34 to 0.77)	0.002
Potting soils/compost	501	62	12.4	902	145	16.1	0.74	0.71	(0.52 to 0.99)	0.040
Reside/work on farm	497	45	9.1	902	106	11.8	0.75	0.78	(0.54 to 1.13)	0.184
Farm animals	496	54	10.9	902	105	11.6	0.93	0.97	(0.68 to 1.39)	0.887

Bold values indicate significant associations (p<0.05)
*Adjusted for age, sex and state; all other OR adjusted for age, sex, state and tobacco smoking (never/past/current).