Yearly changes in FEV1 and DLCO before and after pregnancy
Subject | FEV1
(% pred) | DLCO
(% pred) | ∆FEV1
(mL/year) | ∆FEV1
(%/year) | ∆DLCO
(mL/min/ mm Hg/year) | ∆DLCO
(%/year) | ||||
Pregnancy | Before | Before | After | Before | After | Before | After | Before | After | |
2 | 1.6 (53) | 13 (48) | −231 | −198 | −6.8 | −5.99 | −1.76 | −1.55 | −5.9 | −3.9 |
3 | 2.6 (77) | 20 (82) | −184 | −284 | −4.7 | −7.9 | −0.99 | −0.93 | −2.9 | −2.6 |
4 | 2.8 (78) | 18 (57) | −29 | −173 | −0.27 | −4.2 | −0.3 | −0.71 | −0.69 | −2.0 |
5 | 2.5 (76) | 18 (66) | −546 | −315 | −17.8 | −10.2 | −3.3 | −2.59 | −11.8 | −9.3 |
8 | 3.4 (102) | 17 (57) | −227 | −420 | −6.0 | −11.9 | – | – | – | – |
9 | 2.8 (96) | 19 (72) | −37 | −66 | −0.46 | −1.5 | 0.78 | −0.99 | −3.29 | 3.3 |
10 | 3.3 (115) | 29 (132) | 50 | −48 | 10.8 | −0.87 | 3.7 | -2 | 17.1 | −8.6 |
12 | 2.8 (98) | 19 (89) | −44 | −95 | −0.7 | −2.6 | −0.66 | −0.78 | −2.5 | −3.2 |
13 | 3.4 (104) | – | 21 | −252 | −0.9 | −4.7 | – | – | ||
14 | 2.1 (62) | 15 (63) | −84 | −151 | −1.8 | -4 | −0.53 | −0.81 | −1.88 | −3.0 |
15 | 1.7 (64) | 11 (53) | −96 | −165 | −2.6 | −5.6 | −1.17 | −0.96 | −4.8 | −4.2 |
16 | 2.0 (83) | 17 (87) | −43 | −157 | −0.7 | −6.0 | −0.24 | −0.98 | −0.6 | −4.3 |
Data shown only include measurements taken when not receiving an mTOR inhibitor. Subject numbers correspond to table 1 and the figure 1. ∆FEV1 rate of change of FEV1 (mL/year) and per cent predicted/year (%/year). ∆DLCO rate of change of DLCO (mL/min/mm Hg/year).
FEV1, forced expiratory volume in 1 s.