Table 1

Characteristics of included studies on systematic review and meta-analysis

Author, year,
country
ParticipantsAge
Mean (SD)
InterventionsFEV1
Mean (SD)
Maximal or submaximal test/variables reportedType of complicationsSurgical approach
Prospective cohort studies
 Ambrozin et al,28 2013, Brazil9852.7 (17.2)Lobectomy/ pneumonectomy (repartition not specified)2.3±0.8 LMaximal/timeRespiratory: 75%
Cardiac: 19%
Death: 4%
Other: 2%
Thoracotomy
 Arruda18 2013, Brazil4854.0 (16.7)All major lung resection without details2.3±0.7 LMaximal/timeRespiratory: 98%
Death: 2%
Not specified
 Brunelli, 2008, Italy14 64066.7 (9.3)533 lobectomies/bilobectomies
107 pneumonectomies
85.4%±18.8%Maximal/climbed heightNot reported Thoracotomy
 Brunelli, 2008,27 Italy53667.0 (9.0)440 lobectomies
96 pneumonectomies
85.6±18.9%Maximal/oxygen desaturation
Climbed height
Cardiac: 50%
Respiratory: 47%
Other: 3%
Thoracotomy
 Nikolić et al,25 2008, Croatia10161.1 (8.4)55 lobectomies
14 bilobectomies
17 pneumonectomies
15 others
Complications (n=124) 1.63±0.44 L
No complications (n=170)
1.75±0.49 L
Maximal/time
Oxygen desaturation
Cardiac: 41%
Respiratory: 32%
Other: 27%
Thoracotomy
 Toker et al,26 2008, Turkey15060.0 (10.6)101 lobectomies
27 pneumonectomies
22 wedge resections
Complications (n=31) 2.29±0.69
No complications (n=119)
2.43±0.73
Submaximal/time
Oxygen desaturation
Heart rate change
Respiratory: 62%
Cardiac: 38%
Thoracotomy
 Salahuddin et al,30 2005, Pakistan7852.9 (16.2)All major lung resection without details<1 floor (n=19) 1.3±0.17 L
≥1 floor (n=59) 4.5±2.37 L
Maximal/climbed heightRespiratory: 67%
Cardiac: 33%
Thoracotomy/VATS
 Zurauskas et al,13 2002, Lithuania5262.2 (4.6)35 lobectomies
11 pneumonectomies
6 others
No dataMaximal/climbed heightCardiac: 36%
Respiratory: 59%
Death: 5%
Thoracotomy
 Girish et al,15 2001, USA8366.3 (1.3)31 lobectomies
6 wedge resections
3 pneumonectomies
3 thymectomies
39 others
Complications (n=21) 1.8±0.77 L
No complications (n=62)
2.3±0.82 L
Maximal/climbed height Respiratory: 67%
 Cardiac: 25%
 Death: 8%
Thoracotomy
 Pate et al,29 1996,
 USA
1163.6 (4.9)5 lobectomies
2 segmentectomies
2 wedge resections
1 pneumonectomy
1 other
1.38±0.3 LMaximal/climbed height Respiratory: 71%
 Cardiac: 14.5%
 Death: 14.5%
Thoracotomy
 Holden et al,16 1992, USA1668.5 (8.7)6 lobectomies
4 pneumonectomies
3 wedge resections
3 segmentectomies
Complications (n=5) 1.38±0.08 L
No complications (n=62)
1.44±0.13 L
Maximal/climbed height Respiratory: 53%
 Cardiac: 40%
 Death: 6%
Thoracotomy
Retrospective cohort studies
 Dong et al,19 2017,
 China
17165.0 (9.0)27 wedge resection
122 lobectomies
22 pneunomectomies
Complications (n=124) 1.63±0.44 L
No complications (n=170)
1.75±0.49 L
Submaximal/ Oxygen desaturation
Heart rate change
Climbed height
 Cardiac: 59%
 Respiratory: 36%
 Death: 5%
Thoracotomy/VATS
 Olsen et al,17 1991,
 USA
5460.6 (9.9) 25 lobectomies
 21 wedge resections
 4 pneumonectomies
 4 others
2.41±0.62 LMaximal/climbed height Respiratory: 55%
 Cardiac: 34%
 Other: 9%
 Death: 2%
Thoracotomy
  • FEV1, forced expiratory volume in 1 s; VATS, video-assisted thoracic surgery.