Table 2

MC subtypes in IPF vs non-fibrotic lungs (number of MCs/mm2 tissue area)

Non-fibrotic lung (n=20); number of MCs/mm2 tissue areaIPF (n=17); number of MCs/mm2 tissue areaP value
Chymase only3 (0–39)13 (4–53)0.0003
Tryptase only (MCT)65.5 (1–271)122 (5–374)0.0894
Chymase+ tryptase (MCTC)1 (0–64)3 (1–37)0.0284
  • Median and range shown. Groups compared by Mann-Whitney U test.

  • IPF, idiopathic pulmonary fibrosis; MC, mast cell.