Table 3

Top 10 biological processes altered in septic lungs treated with MSCs

Biological processesFDRCombined score
Torso signalling pathway (GO:0008293)0.000436.33
Positive regulation of transcription from RNA polymerase II promoter (GO:0045944)0.011932.39
Integrin-mediated signalling (GO:0007229)0.002331.64
Regulation of transcription involved in cell fate commitment (GO:0060850)0.000930.26
Regulation of transcription in anterior/posterior axis specification (GO:0044324)0.001229.08
Positive regulation of transcription from RNA polymerase III promoter (GO:0045945)0.004228.45
Regulation of transcription from RNA polymerase II promoter (GO:0060994)0.001528.35
Regulation of SREBP signalling pathway (GO:2000638)0.001528.27
Regulation of transcription from RNA polymerase II promoter (GO:1901213)0.002727.78
Positive regulation of DNA-templated transcription, elongation (GO:0032786)0.004527.7
  • FDR, false discovery rate; GO, gene ontology; MSC, mesenchymal stromal cell.