Table 3

Expression levels of 16 proteins differentially expressed between TB and non-TB

Proteins	Median TB (pg/mL)	25%–75% TB (pg/mL)	Median non-TB (pg/mL)	25%–75% non-TB (pg/mL)	P value	FDR	Ratio	Cohen's d
MIG	2490.5	1121.3–6512.4	609.2	295.9–1312.9	0	0	0.831	0.226
Furin	0	0–5.697	245.18	10.11–352.18	0	0.001	−2.065	−0.195
I-309	5.792	3.058–10.982	1.9	1.087–3.23	0	0.001	1.389	0.847
IL-1 F7	1785.8	1506.6–2021.3	1321.1	1109.3–1657.4	0	0.002	−0.574	−0.105
EGFR	3242	2786–3775	4246	3478–4935	0	0.002	−0.317	−0.789
I-TAC	100.27	61.11–198.06	48.04	28.84–84.45	0	0.003	0.765	0.513
MEP1B	372.76	28.38–756.09	894.8	413.3–1479.9	0	0.006	−1.273	−0.55
Granulysin	514.38	296.66–837.17	945	555.1–1641.4	0	0.013	−0.664	−0.558
MDGA1	206	117.19–258.77	294.83	186.64–553.11	0	0.017	−1.075	−0.486
FAP	5999	5613–7308	7213	6376–8744	0.001	0.025	−0.246	−0.645
FOLR2	1205.8	929.2–1943.5	880.07	469.61–1224.33	0.001	0.025	0.542	0.663
PDGF-CC	69.78	0–316.87	0	0–70.69	0.001	0.025	0.696	0.189
IGFBP-5	0	0–0	51.04	0–785.55	0	0.025	−4.24	−0.177
LYVE-1	767.2	712.2–917.2	694.8	626.1–768.2	0.001	0.029	0.271	0.824
CRIM1	121.69	90.25–168.92	157.89	113.99–238.47	0.001	0.035	−0.659	−0.572
CHI3L1	2922	2527–3503	2293.6	1714.7–3171.7	0.001	0.035	0.265	0.4

Ratio: log2 (fold change); ratio >0, upregulation in TB; ratio <0, upregulation in non-TB.
CHI3L1, chitinase-3-like protein 1; CRIM1, cysteine rich transmembrane BMP regulator 1; EFGR, epidermal growth factor receptor; IL-1 F7, interleukin-1 family member 7 ; FAP, fibroblast activation protein; FDR, false discovery rate; FOLR2, folate receptor beta; I-309, also called CCL1/TCA3; IGFBP-5, insulin-like growth factor-binding protein 5; I-TAC, interferon-inducible T-cell alpha chemoattractant; LYVE1, lymphatic vessel endothelial hyaluronan receptor 1; MDGA1, MAM domain containing glycosylphosphatidylinositol anchor1; MEP1B, meprin A subunit beta; MIG, monokine induced by gamma interferon; PDGF-CC, platelet-derived growth factor-CC.