Definitions used in classifying study participants
| Classification | Definition |
| HC | Negative CXR, no clinical symptoms of tuberculosis, no history of TB, negative IGRAs |
| LTBI | Negative CXR, no clinical symptoms of tuberculosis, no history of TB, positive IGRAs |
| PN | Negative cultures for MTB, negative smears, radiographic suggestive of non-PTB and no history of TB |
| Definite TB | Sputum culture-positive for MTB plus CT suggestive of PTB; or positive smears plus symptoms responding to TB treatment, CT suggestive of PTB |
| Probable TB | No sputum or negative smear and negative MTB, but CT evidence and symptoms responding to TB treatment |
CXR, chest X-ray; HC, healthy control; LTBI, latent tuberculosis infection; MTB, Mycobacterium tuberculosis; PN, pneumonia; PTB, pulmonary tuberculosis.