Table 2

Definitions used in classifying study participants

ClassificationDefinition
HCNegative CXR, no clinical symptoms of tuberculosis, no history of TB, negative IGRAs
LTBINegative CXR, no clinical symptoms of tuberculosis, no history of TB, positive IGRAs
PNNegative cultures for MTB, negative smears, radiographic suggestive of non-PTB and no history of TB
Definite TBSputum culture-positive for MTB plus CT suggestive of PTB; or positive smears plus symptoms responding to TB treatment, CT suggestive of PTB
Probable TBNo sputum or negative smear and negative MTB, but CT evidence and symptoms responding to TB treatment
  • CXR, chest X-ray; HC, healthy control; LTBI, latent tuberculosis infection; MTB, Mycobacterium tuberculosis; PN, pneumonia; PTB, pulmonary tuberculosis.