Variable | Cohort 1 (n=103) | Cohort 2 (n=108) |
Median age (years) | 67 (60–73) | 65 (58–71) |
Male/female (numbers) | 85/18 | 80/28 |
Alive/dead (numbers) | 33/70 | 52/56* |
Mean CT time interval (years) | 1.1±0.4 | 1.0±0.4* |
Antifibrotic use (Y/N) | 33/70 | 74/34** |
Definite UIP pattern on CT (Y/N) | 45/58 | 32/76* |
Baseline FVC (% predicted) | 74.3±20.0 | 75.9±19.6 |
Baseline DLco (% predicted) | 41.3±12.2 | 48.2±14.4 |
Baseline CPI (% predicted) | 50.6±11.4 | 46.2±12.3 |
Data represent mean values with SDs or medians with IQRs unless otherwise indicated.
*P<0.05, **P<0.001.
CPI, Composite Physiological Index; DLco, diffusion capacity for carbon monoxide; FVC, forced vital capacity; N, no; UIP, usual interstitial pneumonia; Y, yes.