Table 2

Between-group differences in primary and secondary outcomes in PTR and PR groups. Intention-to-treat principle

Between-group differences from baseline (95% CI)
PR-PTR (unadjusted)PR-PTR (adjusted)
End rehabilitation†22 weeks from baseline‡End rehabilitation†22 weeks from baseline‡
Primary outcome
 6MWD, min6.3 (−9.8 to 22.5)−11.0 (−34.4 to 12.4)8.3 (−7.7 to 24.3)−3.9 (−27.9 to 19.9)
Secondary outcomes
 30sec-STS, reps0.5 (−0.6 to 1.5)0.4 (−0.7 to 1.4)0.5 (−0.6 to 1.5)0.5 (−0.6 to 1.6)
 CAT, points1.4 (−0.1 to 3.0)−0.5 (−2.6 to 1.5)1.6 (0.1 to 3.3)*−0.2 (−2.1 to 1.8)
HADS
 Anxiety, points1.1 (0.1 to 2.1)*0.2 (−0.9 to 1.4)1.2 (0.2 to 2.3)*0.4 (−0.8 to 1.6)
 Depression, points0.7 (−0.1 to 1.5)−0.2 (−1.3 to 1.0)0.9 (0.1 to 1.7)*−0.2 (−1.3 to 1.0)
 EQ-5D-VAS, points−0.2 (−6.4 to 5.9)0.8 (−5.8 to 7.5)−0.2 (−6.2 to 5.9)1.6 (−5.1 to 8.3)
CCQ
 Function, points0.1 (−0.2 to 0.5)0.1 (−0.2 to 0.5)0.1 (−0.2 to 0.5)0.2 (−0.2 to 0.5)
 Mental, points0.1 (−0.3 to 0.6)−0.1 (−0.4 to 0.3)0.3 (−0.2 to 0.7)0.1 (−0.3 to 0.5)
 Symptoms, points0.2 (−0.1 to 0.5)0.1 (−0.3 to 0.5)0.2 (−0.1 to 0.5)0.1 (−0.2 to 0.5)
 Total, points0.2 (−0.1 to 0.4)0.1 (−0.2 to 0.3)0.2 (−0.1 to 0.5)0.1 (−0.1 to 0.4)
PAL
 Steps per day−283 (−845 to 278)−302 (−1035 to 419)−436 (−1010 to 138)−103 (−886 to 597)
 Sedentary, min9.4 (−35.2 to 51.3)8.6 (−53.8 to 36.6)7.7 (−49.0 to 52.2)14.6 (−32.5 to 58.5)
 Active, min−9.4 (−51.3 to 35.4)−8.6 (−36.6 to 53.8)−7.7 (−52.2 to 49.0)−14.6 (−58.5 to 32.5)
  • Data are mean difference (95% CI).

  • *P value for group mean change differences <0.05.

  • †Complete observations (n) used for the likelihood estimate from end of rehabilitation to baseline (total): 6MWD: (115); 30sec-STS: (115); CAT: (119); HADS: (110); EQ-5d-VAS: (119); CCQ: (119); PAL: (59).

  • ‡Complete observations (n) used for the likelihood estimate from 22 weeks’ follow-up from baseline to baseline (total): 6MWD: (95); 30sec-STS: (95); CAT: (106); HADS: (100); EQ-5d-VAS: (104); CCQ: (106); PAL: (55).

  • CAT, COPD Assessment Test; CCQ, COPD Clinical Questionnaire; EQ-5D, EuroQol 5-Dimension Questionnaire; HADS, Hospital Anxiety and Depression Scale; 6MWD, 6 min walk distance; PAL, physical activity level; PR, pulmonary rehabilitation; PTR, pulmonary tele-rehabilitation; 30sec-STS, 30 s sit-to-stand test; VAS, Visual Analogue Scale.