Table 1

Baseline case characteristics according to patient gender

Case characteristicsAll patients
(n=60)
Female patients
(n=26)
Male patients
(n=34)
P value
Age, mean (SD)61 (15.9)55.2 (13.5)65.5 (16.4)0.012
Smoker, ever37 (62%)12 (46%)25 (74%)0.25
FVC %77.4 (22.7)76.2 (25)78.4 (21)0.73
DLCO %45.8 (24.2)44.2 (17.9)47.1 (14.8)0.51
Bronchoalveolar lavage performed31 (52%)12 (48%)19 (56%)0.53
Exposure (any)14 (24%)4 (15%)10 (29%)0.57
 Birds1 (2%)1 (4%)0
 Asbestos3 (5%)03 (9%)
 Metal2 (3%)1 (4%)1 (3%)
 Wood3 (5%)1 (4%)2 (6%)
Symptom of autoimmunity10 (17%)7 (27%)3 (9%)0.28
 Raynaud’s4 (7%)3 (12%)1 (3%)
 Sicca5 (8%)2 (8%)2 (6%)
 Arthralgias4 (7%)3 (12%)1 (3%)
 Myalgias2 (3%)2 (8%)0
Autoantibody present20 (33%)8 (31%)12 (35%)0.50
 Antinuclear antibody6 (10%)3 (12%)3 (9%)
 Rheumatoid factor5 (8%)3 (12%)2 (6%)
 Other9 (15%)3 (12%)6 (18%)
Family history of ILD‡1 (2%)01 (3%)0.31
Serum aspergillus precipitins present16 (27%)7 (27%)9 (26%)0.97
Pattern on scan0.002
 Definite UIP§10 (17%)2 (8%)8 (24%)
 Probable UIP18 (30%)5 (19%)13 (38%)
 Indeterminate11 (18%)3 (12%)8 (24%)
 Alternate diagnosis21 (35%)16 (62%)5 (15%)
Died during follow-up26 (43%)9 (35%)17 (50%)0.23
Follow-up time (years)4.1 (1.2)4.4 (0.8)3.9 (1.4)0.08
  • DLCO%, diffusion capacity of the lung for carbon monoxide; FVC%, forced vital capacity percent predicted; ILD, interstitial lung disease; UIP, Usual interstitial pneumonia.