Demographic and clinical characteristics of patients based on control status
| Characteristic | Control assessed using e-diary/eCRF (n=2044) | ||
| Controlled (n=418) | Non-controlled (n=1626) | P value | |
| Age, years | 62.8±8.4 | 63.3±7.8 | 0.2497 |
| Men, n (%) | 309 (73.9) | 1227 (75.5) | 0.5164 |
| BMI, kg/m2 | 25.1±5.4 | 25.4±5.5 | 0.3806 |
| Current smoker, n (%) | 150 (35.9) | 627 (38.6) | 0.3148 |
| Duration of COPD, years | 6.3±5.4 | 7.3±5.5 | 0.0007 |
| COPD severity, n (%) | |||
| Severe | 361 (86.4) | 1268 (78.0) | 0.0003 |
| Very severe | 56 (13.4) | 357 (22.0) | |
| ICS users at baseline, n (%) | 280 (67.0) | 1259 (77.4) | <0.0001 |
| COPD exacerbations, n (%) | |||
| 1 | 350 (83.7) | 1226 (75.4) | 0.0013 |
| ≥2 | 63 (15.1) | 378 (23.2) | |
| Baseline COPD symptom score* | 5.2±2.7 | 7.7±2.9 | <0.0001 |
| SGRQ total score | 32.8±15.1 | 49.3±17.6 | <0.0001 |
| Postbronchodilator FEV1, % predicted | 39.1±7.7 | 36.9±8.1 | <0.0001 |
| Postbronchodilator FEV1, mL | 1100±300 | 1000±290 | <0.0001 |
| Postbronchodilator FEV1/FVC, % | 41.7±9.9 | 38.8±9.2 | <0.0001 |
Data are presented as mean (SD) unless otherwise mentioned.
*COPD symptom score based on dyspnoea, sputum colour and use of rescue medication (see online supplementary material 2).
BMI, body mass index; COPD, chronic obstructive pulmonary disease; eCRF, electronic case report form; e-diary, electronic patient diary; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; ICS, inhaled corticosteroids; SGRQ, St. George’s Respiratory Questionnaire.