Sleep study parameters between CPAP and PT
CPAP | PT | Adjusted mean difference* | P value | |
Total AHI, events/hour | 4.0±3.2 | 13.0±13.8 | 8.8 (4.1 to 13.6) | 0.001 |
NREM AHI, events/hour | 3.9±3.8 | 11.0±13.7 | 6.9 (2.1 to 11.7) | 0.006 |
REM AHI, events/hour | 4.6±4.1 | 21.8±19.7 | 16.9 (9.8 to 24.0) | <0.001 |
Supine AHI, events/hour | 5.9±7.2 | 18.5±24.4 | 12.5 (4.3 to 20.7) | 0.004 |
Non-supine AHI, events/hour | 2.6±4.3 | 13.5±16.9 | 10.9 (4.7 to 17.1) | 0.001 |
% total sleep time SaO2 <90% | 0.2±0.8 | 1.1±2.6 | 0.9 (−0.05 to 1.8) | 0.063 |
ODI 3%, events/hour | 0.8±0.9 | 5.9±10.5 | 5.0 (1.3 to 8.6) | 0.009 |
Nadir SaO2,% | 90.2±4.1 | 86.1±7.6 | −4.0 (−6.8 to −1.3) | 0.005 |
Total sleep time | 393.1±66.9 | 402.1±57.2 | 9.5 (−12.9 to 31.8) | 0.394 |
Supine sleep time | 251.2±109.7 | 75.1±104.2 | −171.8 (−215.6 to −128.1) | <0.001 |
Sleep efficiency (%) | 82.9±12.1 | 85.4±9.3 | 2.6 (−1.8 to 6.9) | 0.239 |
Wake after sleep onset (min) | 55.2±40.0 | 41.8±30.4 | −13.5 (−29.4 to 2.4) | 0.094 |
Sleep onset latency (min) | 26.1+54.2 | 26.6+35.4 | −0.1 (−13.9 to 13.7) | 0.991 |
N3, % total sleep time | 16.3±7.2 | 13.3±8.2 | −3.0 (−6.1 to 0.1) | 0.056 |
REM, % total sleep time | 20.7±6.6 | 19.7±6.6 | −0.9 (−3.7 to 1.9) | 0.528 |
Arousal index | 12.6±7.2 | 8.4±4.1 | −4.3 (−6.5 to −2.1) | <0.001 |
*Multivariate model was adjusted to gender, age, race, BMI, randomisation sequence, baseline ESS, baseline AHI, baseline of the respective outcome measure, device’s adherence and device*randomisation sequence.
AHI, Apnoea-Hypopnoea Index; CPAP, continuous positive airway pressure ; N3, Stage 3NREM Sleep; NREM, non-rapid eye movement; ODI, Oxygen Desaturation Index; PT, positional therapy; REM, rapid eye movement; SaO2, oxygen saturation.