Lung function and exercise tolerance
| Home, N=21 | Hospital, N=28 | Adjusted mean difference in change home versus in-hospital (95% CI) | |||
| Baseline | 6 months | Baseline | 6 months | 6 months–baseline | |
| FEV1, L | 0.60±0.16 | 0.63±0.20 | 0.60±0.20 | 0.68±0.30* | −0.05 (−0.14 to 0.03) |
| FVC, L | 2.19±0.55 | 2.23±0.85 | 1.94±0.49 | 2.23±0.90* | −0.31 (−0.67 to 0.05) |
| TLC, L† | 7.4±1.6 | 7.8±1.5 | 7.1±1.3 | 7.3±1.2 | 0.2 (−0.4 to 0.7) |
| RV, L | 4.9±1.3 | 5.2±1.2 | 5.0±1.2 | 4.9±0.9 | 0.4 (−0.2 to 0.9) |
| RV%TLC | 65±7 | 67±10 | 69±7 | 67±9* | 4 (−0.4 to 8) |
| 6MWD, m | 179±93 | 212±100* | 194±85 | 231±90* | −7 (−49 to 34) |
Data are shown as mean±SD. A positive mean difference means an increase from baseline to 6 months for the home compared with the in-hospital group.
*P<0.05.
†Body plethysmography was performed in 16 (home) and 25 (in-hospital) patients, and the 6MWD in 22 (home) and 26 (in-hospital) patients.
FEV1, Forced Expiratory Volume in 1 second; FVC, Forced Vital Capacity; 6MWD, 6 min walking distance; RV, residual volume; TLC, total lung capacity.