Patient age, years | Year 6, 2013–14 | Year 7, 2014–15* | Year 8, 2015–16 | Year 9, 2016–17 | Year 10, 2017–18 | |||||||||||
n | Incidence* | 95% CI | n | Incidence* | 95% CI | n | Incidence* | 95% CI | n | Incidence* | 95% CI | n | Incidence* | 95% CI | ||
All CAP | 538 | 96.3 | 88.4 to 104.8 | 688 | 120.9 | 112.1 to 130.3 | 548 | 95.8 | 88.0 to 104.2 | 744 | 129.3 | 120.2 to 139.0 | 919 | 158.4 | 148.4 to 169.0 | |
16–49 | 91 | 27.3 | 22.0 to 33.5 | 117 | 34.8 | 28.8 to 41.7 | 114 | 33.7 | 27.8 to 40.5 | 112 | 33.0 | 27.1 to 39.7 | 102 | 29.9 | 24.4 to 36.3 | |
50–64 | 93 | 80.2 | 64.7 to 98.2 | 127 | 107.6 | 89.7 to 128.1 | 114 | 94.9 | 78.3 to 114.0 | 145 | 119.7 | 101.0 to 140.8 | 180 | 146.9 | 126.3 to 170.0 | |
65–74 | 105 | 181.3 | 148.3 to 219.5 | 148 | 248.7 | 210.3 to 292.2 | 101 | 164.2 | 133.7 to 199.5 | 131 | 210.4 | 175.9 to 249.6 | 194 | 310.4 | 268.3 to 357.3 | |
75–84 | 145 | 400.6 | 338.0 to 471.3 | 181 | 495.9 | 426.3 to 573.6 | 142 | 386.9 | 325.9 to 456.0 | 199 | 541.3 | 468.7 to 622.0 | 207 | 559.5 | 845.8 to 641.1 | |
≥85 | 104 | 707.5 | 578.1 to 857.2 | 115 | 766.7 | 633.0 to 920.3 | 77 | 505.4 | 398.9 to 631.7 | 157 | 1024·1 | 870.2 to 1197·5 | 236 | 1522·6 | 1334·5 to 1729·7 | |
Pneumococcal CAP | 180 | 32.2 | 27.7 to 37.3 | 200 | 35.2 | 30.5 to 40.4 | 166 | 29.0 | 24.8 to 33.8 | 247 | 42.9 | 37.7 to 48.6 | 282 | 48.6 | 43.1 to 54.6 | |
16–49 | 45 | 13.5 | 9.8 to 18.0 | 46 | 13.7 | 10.0 to 18.3 | 36 | 10.6 | 7.5 to 14.7 | 46 | 13.5 | 9.9 to 18.1 | 41 | 12.0 | 8.6 to 16.3 | |
50–64 | 36 | 31.0 | 21.7 to 43.0 | 40 | 33.9 | 24.2 to 46.2 | 37 | 30.8 | 21.7 to 42.5 | 55 | 45.4 | 34.2 to 59.1 | 60 | 49.0 | 37.4 to 63.0 | |
65–74 | 38 | 65.6 | 46.4 to 90.1 | 48 | 80.7 | 59.5 to 107.0 | 41 | 66.6 | 47.8 to 90.4 | 50 | 80.3 | 59.6 to 105.9 | 69 | 110.4 | 85.9-139-7 | |
75–84 | 28 | 77.3 | 51.4 to 111.8 | 45 | 123.3 | 89.9 to 165.0 | 34 | 92.6 | 64.2 to 129.5 | 59 | 160.5 | 122.2 to 207.0 | 63 | 170.3 | 130.8 to 217.8 | |
≥85 | 33 | 224.5 | 154.5 to 315.3 | 21 | 140.0 | 86.7 to 214.0 | 21 | 137.8 | 85.3 to 210.7 | 37 | 241.4 | 170.0 to 332.7 | 49 | 316.1 | 233.9 to 417.9 | |
PCV7-serotype CAP | 10 | 1.8 | 0.9 to 3.3 | 14 | 2.5 | 1.3 to 4.1 | 12 | 2.1 | 1.1 to 3.7 | 17 | 3.0 | 1.7 to 4.7 | 18 | 3.1 | 1.8 to 4.9 | |
16–49 | 1 | 0.3 | 0.0 to 1.7 | 2 | 0.6 | 0.1 to 2.2 | 3 | 0.9 | 0.2 to 2.6 | 2 | 0.6 | 0.1 to 2.1 | 1 | 0.3 | 0.0 to 1.6 | |
50–64 | 1 | 0.9 | 0.0 to 4.8 | 1 | 0.8 | 0.0 to 4.7 | 2 | 1.7 | 0.2 to 6.0 | 1 | 0.8 | 0.0 to 4.6 | 2 | 1.6 | 0.2 to 5.9 | |
65–74 | 3 | 5.2 | 1.1 to 15.1 | 3 | 5.0 | 1.0 to 14.7 | 3 | 4.9 | 1.0 to 14.2 | 6 | 9.6 | 3.5 to 21.0 | 5 | 8.0 | 2.6 to 18.7 | |
75–84 | 1 | 2.8 | 0.1 to 15.4 | 6 | 16.4 | 6.0 to 35.8 | 2 | 5.4 | 0.7 to 19.7 | 3 | 8.2 | 1.7 to 23.9 | 6 | 16.2 | 6.0 to 35.3 | |
≥85 | 4 | 27.2 | 7.4 to 69.7 | 2 | 13.3 | 1.6 to 48.2 | 2 | 13.1 | 1.6 to 47.1 | 5 | 32.6 | 10.6 to 76.1 | 4 | 25.8 | 7.0 to 66.1 | |
PCV13non7-serotype CAP | 64 | 11.5 | 8.8 to 14.6 | 56 | 9.8 | 7.4 to 12.8 | 51 | 8.9 | 6.6 to 11.7 | 88 | 15.3 | 12.3 to 18.8 | 90 | 15.5 | 12.5 to 19.1 | |
16–49 | 15 | 4.5 | 2.5 to 7.4 | 4 | 1.2 | 0.3 to 3.0 | 7 | 2.1 | 0.8 to 4.3 | 11 | 3.2 | 1.6 to 5.8 | 5 | 1.1 | 0.5 to 3.4 | |
50–64 | 15 | 12.9 | 7.2 to 21.3 | 8 | 6.8 | 2.9 to 13.4 | 11 | 9.2 | 4.6 to 16.4 | 14 | 11.6 | 6.3 to 19.4 | 23 | 18.8 | 11.9 to 28.2 | |
65–74 | 14 | 24.2 | 13.2 to 40.6 | 21 | 35.3 | 21.8 to 54.0 | 14 | 22.8 | 12.4 to 38.2 | 21 | 33.7 | 20.9 to 51.6 | 23 | 36.8 | 23.3 to 55.2 | |
75–84 | 12 | 33.1 | 17.1 to 57.9 | 13 | 35.6 | 19.0 to 60.9 | 8 | 21.8 | 9.4 to 43.0 | 29 | 78.9 | 52.8 to 113.3 | 22 | 59.5 | 37.3 to 90.0 | |
≥85 | 8 | 54.4 | 23.5 to 107.2 | 10 | 66.7 | 32.0 to 122.6 | 11 | 72.2 | 36.0 to 129.1 | 13 | 84.8 | 45.2 to 145.0 | 17 | 109.7 | 63.9 to 175.6 | |
PPV23non13-serotype CAP | 71 | 12.7 | 9.9 to 16.0 | 93 | 16.3 | 13.2 to 20.0 | 73 | 12.8 | 10.0 to 16.0 | 99 | 17.2 | 14.0 to 21.0 | 95 | 16.4 | 13.3 to 20.0 | |
16–49 | 19 | 5.7 | 3.4 to 8.9 | 27 | 8.0 | 5.3 to 11.7 | 20 | 5.9 | 3.6 to 9.1 | 23 | 6.8 | 4.3 to 10.2 | 21 | 6.1 | 3.8 to 9.4 | |
50–64 | 16 | 13.8 | 7.9 to 22.4 | 19 | 16.1 | 9.7 to 25.1 | 19 | 15.8 | 9.5 to 24.7 | 21 | 17.3 | 10.7 to 26.5 | 20 | 16.3 | 10.0 to 25.2 | |
65–74 | 13 | 22.5 | 12.0 to 38.4 | 17 | 28.6 | 16.6 to 45.7 | 16 | 26.0 | 14.9 to 42.2 | 20 | 32.1 | 19.6 to 49.6 | 22 | 35.2 | 22.1 to 53.3 | |
75–84 | 13 | 35.9 | 19.1 to 61.4 | 21 | 57.5 | 35.6 to 87.9 | 12 | 32.7 | 16.9 to 57.1 | 21 | 57.1 | 35.4 to 87.3 | 19 | 51.4 | 30.9 to 80.2 | |
≥85 | 10 | 68.0 | 32.6 to 125.1 | 9 | 60.0 | 27.4 to 113.9 | 6 | 39.4 | 14.4 to 85.7 | 14 | 91.3 | 49.9 to 153.2 | 13 | 83.9 | 44.7 to 143.4 | |
Non-vaccine-serotype CAP | 50 | 9.0 | 6.6 to 11.8 | 55 | 9.7 | 7.3 to 12.6 | 47 | 8.2 | 6.0 to 10.9 | 70 | 12.2 | 9.5 to 15.4 | 99 | 17.1 | 13.9 to 20.8 | |
16–49 | 12 | 3.6 | 1.9 to 6.3 | 15 | 4.5 | 2.5 to 7.4 | 10 | 3.0 | 1.4 to 5.4 | 13 | 3.8 | 2.0 to 6.5 | 13 | 3.8 | 2.0 to 6.5 | |
50–64 | 9 | 7.8 | 3.5 to 14.7 | 13 | 11.0 | 5.9 to 18.8 | 7 | 5.8 | 2.3 to 12.0 | 21 | 17.3 | 10.7 to 26.5 | 19 | 15.5 | 9.3 to 24.2 | |
65–74 | 12 | 20.7 | 10.7 to 36.2 | 13 | 21.8 | 11.6 to 37.4 | 11 | 17.9 | 8.9 to 32.0 | 12 | 19.3 | 10.0 to 33.7 | 25 | 40.0 | 25.9 to 59.0 | |
75–84 | 4 | 11.0 | 3.0 to 28.3 | 11 | 30.1 | 15.0 to 53.9 | 11 | 30.0 | 15.0 to 53.6 | 16 | 43.5 | 24.9 to 70.7 | 22 | 59.5 | 37.3 to 90.0 | |
≥85 | 13 | 88.44 | 47.1 to 151.2 | 3 | 20.0 | 4.1 to 58.4 | 8 | 52.5 | 22.7 to 103.4 | 8 | 52.2 | 22.5 to 102.8 | 20 | 129.0 | 78.8 to 199.3 |
PCV7-serotype CAP: CAP due to serotypes included in PCV7; PCV13non7-serotype CAP: CAP due to serotypes included in PCV13, excluding serotypes also included in PCV7; PPV23non13-serotype CAP: CAP due to serotypes included in PPV23, excluding serotypes also included in PCV13; non-vaccine-serotype CAP: CAP due to a) any non-PCV13-serotype, non-PPV23-serotype and b) untyped pneumococcal cases—blood culture or BINAX urinary antigen detection positive without subsequent serotype identification, or Bio-plex24 assay positive for cell wall polysaccharide only.
*Per 100 000 population.
PCV, pneumococcal conjugate vaccine.