Table 3

Associations of NREM and REM IFL with SBP and DBP

% Change in SBP (95% CI)*P value% Change in DBP (95% CI)*P value
NREM IFL
 Unadjusted model (n=1847)−1.5 (−2.3 to −0.8)<0.001−0.6 (−1.2 to 0.04)0.06
 Model 1 (n=1813)−0.8 (−1.5 to −0.1)0.04−0.6 (−1.2 to 0.07)0.08
 Model 2 (n=1802)−0.8 (−1.5 to −0.1)0.03−0.7 (−1.3 to -0.1)0.03
 Model 3 (n=1754)−0.8 (−1.6 to −0.1)0.02−0.8 (−1.4 to −0.1)0.02
REM IFL
 Unadjusted model (n=1811)−0.9 (−1.7 to −0.2)0.02−0.1 (−0.7 to 0.5)0.76
 Model 1 (n=1778)−0.3 (-1.0 to 0.4)0.41−0.2 (−0.8 to 0.5)0.60
 Model 2 (n=1767)−0.3 (−1.0 to 0.4)0.36−0.2 (−0.8 to 0.4)0.50
 Model 3 (n=1713)−0.2 (−0.9 to 0.6)0.60−0.1 (−0.7 to 0.6)0.78

  • Model 1: Adjusted for age, sex, race/ethnicity, body mass index (kg/m2), smoking status, cigarette pack-years, alcohol use, periodic limb movement, education level, % of time spent in N3 and N4 sleep.

  • Model 2: Model 1+hypoxic burden ((%·min)/hour).

  • Model 3: Model 2+ odds ratio product.

  • *All results reported per SD increment of natural log-transformed NREM and REM IFL.

  • DBP, diastolic blood pressure; IFL, inspiratory flow limitation; NREM, non-rapid eye movement; REM, rapid eye movement;SBP, systolic blood pressure.