Table 3

Proportions with expiratory airflows at 25 years of age <5th centile contrasted between EP/ELBW and control groups and between BPD and no BPD groups within the EP/ELBW cohort

Flow variableEP/ELBW
n=164
Control
n=130
OR (95% CI), P value*BPD
n=65
No BPD
n=99
OR (95% CI), P value*
FEV1 26 (42)2 (3)13.8 (4.14 to 46.1), <0.00134 (22)20 (20)2.24 (1.07 to 4.63), 0.03
FVC7 (11)2 (3)3.08 (0.84 to 11.4), 0.099 (6)5 (5)1.92 (0.56 to 6.53), 0.30
FEV1:FVC38 (63)10 (13)5.26 (2.71 to 10.2), <0.00149 (32)31 (31)1.94 (1.10 to 3.44), 0.022
FEF25%−75% 46 (76)8 (11)9.06 (4.52 to 18.1), <0.00158 (38)38 (38)2.37 (1.27 to 4.41), 0.006
  • Data are % (n), unless otherwise specified.

  • *From regression models using generalised estimating equations to allow for multiple births.

  • BPD, bronchopulmonary dysplasia; EP/ELBW, extremely preterm/extremely low birth weight; FEF25%−75%, airflow between 25% and 75% of the vital capacity.