Table 1

Frequency of clinical variables in paediatrics patients (aged 6–18 years) with sickle cell anaemia (SCA) from the UK (n=101) and Nigeria (NIG) (n=154)

VariableSCA UK (%)SCA NIG (%)P value
Current hydroxyurea treatment47.50.6<0.001
At least three pain crises in the last year†24.749.3<0.001
Previous acute chest syndrome‡34.521.40.02
  • *Parent report or medical record evidence of physician-diagnosed asthma.

  • †Pain crises requiring analgesic therapy for at least 24 hours.

  • ‡Fever and/or respiratory symptoms, accompanied by a new pulmonary infiltrate on a chest X-ray.22