Abstract P262 Table 1

Multivariate Cox regression analysis of survival in patients with advanced COPD

HRSECIp-value
Age at first CRA (years)1.050.021.02 – 1.08<0.001
FEV1 (L) 0.54 0.24 0.23 – 1.28 0.16
MRC dyspnoea scale grade 0.94 0.24 0.8 – 1.54 0.81
4m gait speed (m/s) 1.38 0.18 1.07 – 1.79 0.01
BMI (kg/m2) 1.03 0.01 1.01 – 1.06 0.01
Home oxygen use No 1
Yes 1.27 0.35 0.74 – 2.17 0.39
COPD exacerbation(s) in previous 12 months No 1
Yes 3.12 1.87 0.96 – 10.11 0.06
Comorbidity present No 1
Yes 1.59 0.69 0.68 – 3.74 0.28
  • Covariates: high to low except for 4m gait speed and BMI where lower gait speed and BMI are associated with increased mortality

  • BMI = body mass index; FEV1= Forced expiratory volume in one second; MRC = Medical Research Council dyspnoea scale grade