The incidence rate ratios (IRR) of general practitioner (GP) consultations, respiratory events, and adverse-medication events, in the risk period after an inhaler switch compared with stable periods
Event | Number of patients | Number of events in 3-month risk period | Number of events in control period | IRR | 95% CI |
GP consultation | 50 289 | 143 602 | 926 991 | 1.00 | 0.99 to 1.01 |
Non-specific respiratory | 51 659 | 27 772 | 187 618 | 0.96 | 0.94 to 0.97 |
Adverse-medication | 3258 | 573 | 3520 | 1.06 | 0.97 to 1.15 |
Switches could be between brand-to-generic, brand-to-brand, generic-to-generic or generic-to-brand.
DPI, dry powdered inhaler; MDI, metered-dose inhaler.