Patient demographics, clinical characteristics and prior treatments
Patients (N=135) | |
Age (mean±SD) | 69.1 (10.5) |
Male | 59 (43.7) |
Smoking status | |
Never | 82 (60.7) |
Ex-smoker | 23 (17.0) |
Current | 30 (22.2) |
Comorbidities | |
Cardiovascular disease | 32 (23.7) |
Diabetes mellitus | 13 (9.6) |
Stroke | 12 (8.9) |
Treatment | |
Inhaled bronchodilators | 88 (65.2) |
Inhaled corticosteroids | 59 (43.7) |
Inhaled antibiotics | 6 (4.4) |
Chronic macrolide therapy | 31 (23.0) |
FEV1 (% predicted) (mean±SD) | 78.3 (28.3) |
FVC (% predicted) (mean±SD) | 94.3 (27.0) |
BMI (kg/m2) (mean±SD) | 25.9 (5.6) |
Aetiology | |
Idiopathic | 61 (45.2) |
Postinfective | 22 (16.3) |
Post-tuberculosis | 12 (8.9) |
COPD | 12 (8.9) |
Rheumatoid arthritis | 6 (4.4) |
CTD | 4 (3.0) |
ABPA | 4 (3.0) |
Primary ciliary dyskinesia | 3 (2.2) |
Inflammatory bowel disease | 3 (2.2) |
Asthma | 3 (2.2) |
Haematological malignancy-associated immunodeficiency | 2 (1.5) |
Young syndrome | 2 (1.5) |
Specific antibody deficiency | 1 (0.7) |
Exacerbations in previous 12 months | |
0 | 24 (17.8) |
1 | 28 (20.7) |
2 | 15 (11.1) |
3 | 20 (14.8) |
≥4 | 48 (35.6) |
BSI (mean±SD) | 8.0 (4.3) |
FACED (mean±SD) | 2.4 (1.5) |
Data are expressed by n (%) as otherwise is indicated
ABPA, allergic bronchopulmonary aspergillosis ; BMI, body mass index; BSI, Bronchiectasis Severity Index; COPD, chronic obstructive pulmonary disease; CTD, connective tissue disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.