Index | SCA group | Controls | Mean difference (95% CI) SCA−controls |
N (% male) | 112 (59%) | 377 (55%) | |
Age (years) | 11.2 (3.3) | 9.5 (1.6) | 1.6* (1.2 to 2.1) |
Height z-score | −1.16 (1.41) | 0.33 (1.11) | −1.50* (−1.75 to −1.25) |
BMI z-score | −1.47 (1.07) | −0.20 (1.10) | −1.28* (−1.51 to −1.04) |
FEV1 z-score | −1.48 (1.01) | −0.16 (0.79) | −1.33* (−1.51 to −1.15) |
FEV1% predicted | 80.2 (13.1) | 97.9 (10.2) | −17.7%* (−20.0 to −15.3) |
FVC z-score | −1.35 (1.03) | −0.09 (0.83) | −1.26* (−1.44 to −1.07) |
FVC% predicted | 83.0 (13) | 98.8 (10.7) | −15.8* (−18.3 to −13.5) |
FEV1/FVC z-score | −0.50 (0.80) | −0.17 (0.71) | −0.33** (−0.48 to −0.18) |
Results are presented as mean (SD), unless otherwise specified.
BMI and height z-scores based on WHO 2007 growth charts.7
Spirometry z-scores and % predicted values based on Global Lung Function Initiative 2012 equations for African Americans.8
*p<0.0001; **p<0.01.
BMI, body mass index.