Table 3

Incidence rate ratio of invasive pneumococcal disease (IPD) per PCV10/13 year compared with 2009, 13 sites: SpIDnet/I-MOVE+ multicentre study

Serotypes (group)2011 (year 1)2012 (year 2)2013 (year 3)2014 (year 4)2015 (year 5)
All types0.88 (0.84–0.93)0.88 (0.85–0.92)0.86 (0.79–0.93)0.80 (0.72–0.89)0.91 (0.81–1.03)
PCV70.50 (0.42–0.60)0.40 (0.30–0.51)0.32 (0.23–0.44)0.25 (0.18–0.36)0.23 (0.16–0.33)
PCV13non7*0.91 (0.82–1.02)0.81 (0.72–0.92)0.72 (0.60–0.86)0.60 (0.46–0.77)0.62 (0.47–0.81)
 PCV10non7†0.87 (0.72–1.05)0.79 (0.66–0.94)0.56 (0.43–0.72)0.44 (0.32–0.61)0.27 (0.18–0.41)
 PCV13non10‡0.95 (0.85–1.05)0.83 (0.73–0.94)0.81 (0.65–0.99)0.68 (0.53–0.87)0.81 (0.62–1.05)
  Serotype 30.93 (0.80–1.08)0.90 (0.78–1.06)0.98 (0.79–1.22)0.89 (0.69–1.16)1.03 (0.81–1.31)
  Serotype 19A1.13 (0.95–1.34)1.06 (0.82–1.37)0.98 (0.69–1.38)0.77 (0.56–1.06)0.87 (0.56–1.06)
NonPCV131.10 (1.02–1.19)1.28 (1.16–1.42)1.35 (1.17–1.56)1.35 (1.17–1.57)1.63 (1.39–1.92)
 PPV23 nonPCV13§1.09 (0.91–1.30)1.19 (1.05–1.36)1.23 (1.11–1.37)1.23 (1.12–1.36)1.53 (1.39–1.68)
 Non-vaccine¶1.15 (0.96–1.39)1.47 (1.23–1.75)1.54 (1.25–1.91)1.52 (1.20–1.91)1.78 (1.41–2.24)
  • *Serotypes 1, 3, 5, 6A, 7F and 19A.

  • †Serotypes 1, 5 and 7F.

  • ‡Serotypes 3, 6A and 19A.

  • §Serotypes 2, 8, 9N, 10A, 11A, 12F, 15B, 17F, 20, 22F and 33F.

  • ¶Serotypes not in PPV23 and not in PCV13.