Loved onesBaselineFollow-up
Intervention n=80Control n=69B coefficient95% CIP valuesIntervention n=78Control n=69B coefficient95% CIP values
HADS-A6.2 (4.3)6.7 (4.3)–0.21–1.59 to 1.170.76§5.2 (3.6)6.7 (4.8)–1.25–2.33 to  – 0.18 0.02
HADS-D3.9 (3.6)4.6 (4.2)–0.65–1.93 to  0.630.31§3.6 (3.6)4.8 (4.7)–0.51–1.41 to 0.390.27**
  • Descriptive statistics presented as mean (SD). 

  • *Linear regression analysis adjusted for age.

  • †Linear regression analysis adjusted for baseline HADS-A score and age. 

  • ‡Linear regression analysis adjusted for baseline HADS-D score and age. 

  • §Linear regression analysis adjusted for gender. 

  • ¶Linear regression analysis adjusted for baseline HADS-A score and gender. 

  • **Linear regression analysis adjusted for baseline HADS-D score and age.

  • HADS-A, Hospital Anxiety and Depression Scale, anxiety subscale; HADS-D, Hospital Anxiety and Depression Scale, depression subscale.