Table 2

Geometric mean cough frequency (coughs/hour) and the ratio (omeprazole:placebo) of geometric means at the end of treatment, adjusted for baseline cough frequency (complete-case analysis set; n=40)

 Omeprazole (n=20) Placebo (n=20) Baseline geometric mean (95% CI) End of treatment geometric mean (95% CI) Baseline geometric mean (95% CI) End of treatment geometric mean (95% CI) Ratio of geometric means at end of treatment, adjusted for baseline (95% CI) 24 hours 8.2 (5.4 to 12.7) 4.6 (2.4 to 8.7) 9.1 (6.8 to 12.2) 8.3 (5.3 to 12.9) 0.609 (0.340 to 1.093) Awake/daytime 10.8 (6.8 to 17.0) 6.1 (3.2 to 11.8) 11.8 (8.9 to 15.8) 10.7 (6.7 to 17.2) 0.629 (0.354 to 1.119) Asleep/night-time 1.7 (0.9 to 3.3) 1.1 (0.6 to 2.0) 2.3 (1.1 to 4.7) 2.1 (1.2 to 3.7) 0.553 (0.267 to 1.146)