Characteristics of individuals who attended the LHC, stratified by lung cancer risk
| Variable | All | Lung cancer risk | P value | |
| High (PLCO ≥1.51%) | Low (PLCO <1.51%) | |||
| Number of attendees (%) | 2541 | 1429 (56.2) | 1112 (43.8) | – |
| Mean age (years±SD) | 64.1 (5.5) | 64.7 (5.4) | 63.4 (5.5) | * |
| Sex M/F (F%) | 1245/1296 (51.0) | 706/723 (50.6) | 539/573 (51.5) | 0.64 |
| Median IMD rank (IQR) | 2873 | 2866 (3994) | 3109 (8345) | * |
| BMI (%) | ||||
| < 18.5 | 42 (1.7) | 33 (2.3) | 9 (0.8) | * |
| 18.5 – 24.9 | 531 (20.9) | 353 (24.7) | 178 (16.0) | * |
| 25 – 29.9 | 982 (38.7) | 541 (37.9) | 441 (39.7) | * |
| 30 – 39.9 | 875 (34.4) | 460 (32.2) | 415 (37.3) | |
| ≥ 40 | 111 (4.4) | 42 (2.9) | 69 (6.2) | |
| Education (%) | ||||
| Less than ‘O’ level | 1567 (61.7) | 998 (69.8) | 569 (51.2) | * |
| ‘O’ level | 511 (20.1) | 255 (17.9) | 256 (23.0) | * |
| ‘A’ level | 106 (4.2) | 49 (3.4) | 57 (5.1) | |
| University/college | 213 (8.4) | 84 (5.9) | 129 (11.6) | |
| University degree | 91 (3.6) | 31 (2.2) | 60 (5.4) | |
| Postgrad/professional | 53 (2.1) | 12 (0.8) | 41 (3.7) | |
| Smoking status (%) | ||||
| Current | 891 (35.1) | 754 (52.8) | 137 (12.3) | * |
| Former | 1650 (64.9) | 675 (47.2) | 975 (87.7) | |
| Smoking exposure (mean±SD) | ||||
| Duration (years) | 34.6 (14.7) | 43.8 (8.2) | 22.8 (12.6) | |
| Cigs/days | 20.4 (13.0) | 24.0 (12.9) | 15.8 (11.5) | |
| Pack-years | 36.7 (27.8) | 51.6 (26.8) | 17.7 (14.2) | |
| Spirometry (mean ±SD) | ||||
| FEV1 | 2.3 (0.8) | 2.1 (0.7) | 2.6 (0.8) | |
| % predicted FEV1 | 90.1 (25.0) | 84.0 (24.3) | 98.0 (23.6) | |
| FVC | 3.3 (1.0) | 3.1 (1.0) | 3.4 (1.0) | |
| % predicted FVC | 102.6 (24.9) | 99.4 (24.5) | 106.6 (24.7) | |
| FEV1/FVC ratio | 70.8 (10.6) | 67.8 (11.0) | 74.7 (8.7) | |
| Airflow obstruction | ||||
| Yes (%) | 944 (37.2) | 716 (50.1) | 228 (20.5) | |
| COPD/emphysema | ||||
| Yes (%) | 566 (22.3) | 471 (33.0) | 95 (8.5) | |
| FH lung cancer | ||||
| Yes (%) | 553 (21.8) | 392 (27.4) | 161 (14.5) | |
| MRC dyspnoea score (%) | ||||
| 1 | 1791 (70.5) | 920 (64.4) | 871 (78.3) | |
| 2 | 494 (19.4) | 310 (21.7) | 184 (16.6) | |
| 3 | 163 (6.4) | 123 (8.6) | 40 (3.6) | |
| 4 | 91 (3.6) | 74 (5.2) | 17 (1.5) | |
| 5 | 2 (0.1) | 2 (0.1) | 0 (0) | |
| Performance status (%) | ||||
| 0 | 1552 (61.1) | 768 (53.7) | 784 (70.5) | |
| 1 | 763 (30.0) | 481 (33.7) | 282 (25.4) | |
| 2 | 187 (7.4) | 152 (10.6) | 35 (3.1) | |
| 3 | 38 (1.5) | 28 (2.0) | 10 (1.0) | |
| 4 | 1 (0.0) | 0 (0) | 1 (0.0) | |
*P value <0.0001.
BMI, body mass index; FH, family history; IMD, index of multiple deprivation; LHC, lung health check; MRC, Medical Research Council.