Table 1

Characteristics of individuals who attended the LHC, stratified by lung cancer risk

VariableAllLung cancer riskP value
High
(PLCO ≥1.51%)
Low
(PLCO <1.51%)
Number of attendees (%)25411429 (56.2)1112 (43.8)
Mean age (years±SD)64.1 (5.5)64.7 (5.4)63.4 (5.5)*
Sex M/F (F%)1245/1296 (51.0)706/723 (50.6)539/573 (51.5)0.64
Median IMD rank (IQR)28732866 (3994)3109 (8345)*
BMI (%)
 < 18.542 (1.7)33 (2.3)9 (0.8)*
 18.5 – 24.9531 (20.9)353 (24.7)178 (16.0)*
 25 – 29.9982 (38.7)541 (37.9)441 (39.7)*
 30 – 39.9875 (34.4)460 (32.2)415 (37.3)
 ≥ 40111 (4.4)42 (2.9)69 (6.2)
Education (%)
 Less than ‘O’ level1567 (61.7)998 (69.8)569 (51.2)*
 ‘O’ level511 (20.1)255 (17.9)256 (23.0)*
 ‘A’ level106 (4.2)49 (3.4)57 (5.1)
 University/college213 (8.4)84 (5.9)129 (11.6)
 University degree91 (3.6)31 (2.2)60 (5.4)
 Postgrad/professional53 (2.1)12 (0.8)41 (3.7)
Smoking status (%)
  Current891 (35.1)754 (52.8)137 (12.3)*
 Former1650 (64.9)675 (47.2)975 (87.7)
Smoking exposure (mean±SD)
  Duration (years)34.6 (14.7)43.8 (8.2)22.8 (12.6)
  Cigs/days20.4 (13.0)24.0 (12.9)15.8 (11.5)
 Pack-years36.7 (27.8)51.6 (26.8)17.7 (14.2)
Spirometry (mean ±SD)
  FEV1 2.3 (0.8)2.1 (0.7)2.6 (0.8)
  % predicted FEV1 90.1 (25.0)84.0 (24.3)98.0 (23.6)
  FVC3.3 (1.0)3.1 (1.0)3.4 (1.0)
  % predicted FVC102.6 (24.9)99.4 (24.5)106.6 (24.7)
  FEV1/FVC ratio70.8 (10.6)67.8 (11.0)74.7 (8.7)
Airflow obstruction
  Yes (%)944 (37.2)716 (50.1)228 (20.5)
COPD/emphysema
  Yes (%)566 (22.3)471 (33.0)95 (8.5)
FH lung cancer
  Yes (%)553 (21.8)392 (27.4)161 (14.5)
MRC dyspnoea score (%)
 11791 (70.5)920 (64.4)871 (78.3)
 2494 (19.4)310 (21.7)184 (16.6)
 3163 (6.4)123 (8.6)40 (3.6)
 491 (3.6)74 (5.2)17 (1.5)
 52 (0.1)2 (0.1)0 (0)
Performance status (%)
 01552 (61.1)768 (53.7)784 (70.5)
 1763 (30.0)481 (33.7)282 (25.4)
 2187 (7.4)152 (10.6)35 (3.1)
 338 (1.5)28 (2.0)10 (1.0)
 41 (0.0)0 (0)1 (0.0)
  • *P value <0.0001.

  • BMI, body mass index; FH, family history; IMD, index of multiple deprivation; LHC, lung health check; MRC, Medical Research Council.