Table 2

Results of FBAT homogeneity test in the EGEA and SLSJ samples for SNPs detected in EGEA with p≤5.10⁻³

Chromosome	SNP	Gene	Location	Position* (kb)	MAF†	EGEA	SLSJ	EGEA+SLSJ‡
Chromosome	SNP	Gene	Location	Position* (kb)	MAF†	P values	P values	P values
1	rs10924249	KIF26B	flanking_3UTR	243837	0.18	0.004	0.302	0.059
2	rs6736802	KIF5C	flanking_5UTR	149566	0.43	0.002	0.320	0.056
2	rs6435220	KIF5C	flanking_5UTR	149569	0.31	0.003	0.659	0.032
4	rs1460354	ATP8A1	Intron	42266	0.22	0.001	0.115	6.0E-04
4	rs13124088	ATP8A1	Intron	42280	0.20	0.005	0.227	0.004
4	rs17448506	ATP8A1	Intron	42343	0.27	1.7E-05	0.133	1.2E-05
6	rs160666	WRNIP1	flanking_3UTR	2719	0.32	0.003	0.398	0.041
8	rs2279444	KIF13B	Intron	29053	0.15	0.005	0.400	0.006
9	rs2253304	ABCA1	Intron	106658	0.27	0.004	0.003	6.1E-05
9	rs2253182	ABCA1	Intron	106659	0.27	0.004	0.005	9.2E-05
9	rs2253175	ABCA1	Intron	106660	0.27	0.004	0.004	7.2E-05
9	rs2253174	ABCA1	Intron	106660	0.27	0.004	0.004	7.2E-05
9	rs2230805	ABCA1	Coding	106663	0.25	0.005	0.017	2.0E-04
11	rs762667	MYO7A	Coding	76546	0.38	0.002	0.446	0.003
16	rs2914819	ATP2C2	Intron	83026	0.19	0.003	0.353	0.0018
17	rs7225157	DNAH9§	Intron	11621	0.17	8.1E-04	0.038	6.8E-05
18	rs12458154	ATP9B	Intron	75187	0.28	0.002	0.551	0.0047
20	rs6067867	ATP9A	Intron	49698	0.46	0.005	0.376	0.0056
20	rs6067892	ATP9A	Intron	49731	0.47	0.002	0.410	0.0036
20	rs1475670	ATP9A	Intron	49777	0.50	0.004	0.058	7.0E-04

Significant results are in bold.
*SNP position in kilobase (dbSNP, build 37.1).
†Minor Allele Frequency estimated in EGEA.
‡Combined analysis of the EGEA and SLSJ samples using the Stouffer’s Z-score method.
§Previously detected by our positional cloning.14
EGEA, Epidemiological study on the Genetics and Environment of Asthma; FBAT, Family-Based Association Test; SLSJ, Saguenay-Lac-Saint-Jean; SNP, single-nucleotide polymorphism.