Phenotypic features of genotyped siblings having BHR in EGEA and SLSJ asthma-ascertained families
| EGEA | SLSJ | |
| Siblings (n) | 304 | 145 |
| Age (years), mean (SD) | 16.1 (8.1) | 20.3 (10.3) |
| Sex, n (%) women | 132 (43.4) | 76 (52.4) |
| Asthma, n (%) | 181 (59.5) | 138 (95.2) |
| Age at asthma onset (years), mean (SD) | 7.4 (7.7) | 9.4 (9.3) |
| Allergic sensitisation*, n (%) | 228 (76.0) | 121 (85.8) |
| ETS exposure, n (%) | 176 (57.9) | 93 (64.1) |
*Allergic sensitisation: a positive response of skin prick test to at least one allergen.
BHR, bronchial hyper-responsiveness; EGEA, Epidemiological study on the Genetics and Environment of Asthma; ETS, environmental tobacco smoke; SLSJ, Saguenay-Lac-Saint-Jean.