Factors associated with time to death, multivariate explanatory extended Cox models
| Cox model | Extended Cox model | |||||
| HR | 95% CI | P values | HR | 95% CI | P values | |
| Predictive variables | ||||||
| Zubrod 2–4 vs 0–1 | 4.4 | 2.55 to 7.60 | <0.001 | 3.02 | 1.83 to 5.00 | <0.001 |
| Time from diagnosis to procedure (weeks) | 0.998 | 0.996 to 0.9996 | 0.02 | |||
| Comorbidities: cardiovascular | 1.76 | 1.00 to 3.08 | 0.05 | |||
| Initial treatment type | ||||||
| Surgery | 3.54 | 1.60 to 7.81 | 0.002 | |||
| Chemotherapy | 2.98 | 1.47 to 6.05 | 0.002 | |||
| Radiation therapy | 2.62 | 1.15 to 5.99 | 0.02 | |||
| No treatment | <ref> | |||||
| Obstruction type of most proximal location | ||||||
| Endobronchial | <ref> | |||||
| Extrinsic | 2.63 | 1.54 to 4.50 | <0.001 | |||
| Mixed | 2.35 | 1.13 to 4.86 | 0.02 | |||
| Explanatory variables | ||||||
| Postprocedure treatment | ||||||
| Chemotherapy | 0.42 | 0.26 to 0.69 | 0.001 | 0.51 | 0.32 to 0.81 | 0.004 |
| Time-varying covariates | ||||||
| Utility | 0.003 | 0.001 to 0.02 | <0.001 | |||
| Lower respiratory tract infection | 3.79 | 1.13 to 12.71 | 0.03 | |||