Table 2

Estimates of parameters calculated from the LTBR

Name of variable (units, if applicable)Index case disease typeSymbolValue95% CIs
Number of contacts screened per index caseETB Embedded Image 2.50(2.41 to 2.59)
PTB Embedded Image 3.86(3.72 to 4.00)
Number of contacts found with TB per index caseETB Embedded Image 0.0196(0.0119 to 0.0273)
PTB Embedded Image 0.0938(0.0774 to 0.110)
Proportion of contacts with TB that have ETBETB Embedded Image 0.486(0.329 to 0.643)
PTB Embedded Image 0.337(0.278 to 0.396)
Number of contacts found with LTBI per index caseETB Embedded Image 0.119(0.104 to 0.134)
PTB Embedded Image 0.471(0.428 to 0.514)
Proportion of index contact’s with LTBI that are childrenETB Embedded Image 0.206Not varied
PTB Embedded Image 0.360Not varied
Proportion of contacts with LTBI that begin PT, adult contactETB Embedded Image 0.611(0.510 to 0.712)
PTB Embedded Image 0.666(0.604 to 0.728)
Proportion of contacts with LTBI that begin PT, child contactETB Embedded Image 0.931(0.838 to 1.02)
PTB Embedded Image 0.969(0.922 to 1.02)
Proportion of contacts starting PT that complete PT, adult contactETB Embedded Image 0.875(0.793 to 0.957)
PTB Embedded Image 0.803(0.742 to 0.864)
Proportion of contacts starting PT that complete PT, child contactETB Embedded Image 0.81(0.638 to 0.982)
PTB Embedded Image 0.906(0.845 to 0.967)
Mean symptomatic period of PTB cases not found through contact tracing (days)N/A Embedded Image 110(103 to 117]
Mean symptomatic period of PTB cases found through contact tracing (days)N/A Embedded Image 76.6(58.5 to 94.7)
Mean symptomatic period of PTB cases (days)N/A Embedded Image 109(102 to 116)
Mean symptomatic period of ETB cases not found through contact tracing (days)N/A Embedded Image 181(166 to 196)
Mean symptomatic period of ETB cases found through contact tracing (days)N/A Embedded Image 152(15.0 to 289)
Mean symptomatic period of all cases (days) N/A Embedded Image 147(139 to 155)
  • All parameters are chosen from a normal distribution.

  • ETB, non-pulmonary and non-laryngeal TB; LTBI, latent Mycobacterium tuberculosis infection; LTBR, London TB report; PT, preventive therapy; PTB, pulmonary or laryngeal TB.