Table 4

HADS, cancer worry and AQoL-8D over time and between groups

Month	Randomised group	N	Mean	SD	Min	Max	LS mean	LS Mean difference	Lower 95% CL	Upper 95% CL	P-value for difference	P-value for difference rank analysis
Anxiety
0	Control	268	5.6	4.1	0.0	21.0
0	Intervention	269	5.7	3.9	0.0	21.0
1	Control	223	5.3	4.2	0.0	18.0	5.5
1	Intervention	234	5.3	4.0	0.0	20.0	5.3	−0.2	−0.7	0.3	0.3954	0.6054
12	Control	204	5.2	4.2	0.0	18.0	5.6
12	Intervention	212	5.3	4.1	0.0	19.0	5.4	−0.1	−0.6	0.4	0.6083	0.5179
Depression
0	Control	268	4.4	3.8	0.0	20.0
0	Intervention	269	4.1	3.4	0.0	19.0
1	Control	223	4.3	4.1	0.0	21.0	4.2
1	Intervention	234	3.9	3.5	0.0	16.0	3.9	−0.3	−0.7	0.1	0.1557	0.1218
12	Control	204	4.4	4.1	0.0	21.0	4.2
12	Intervention	212	3.9	3.5	0.0	19.0	4.0	−0.2	−0.7	0.2	0.3672	0.3344
Cancer worry
0	Control	268	3.4	3.2	0.0	17.0
0	Intervention	269	3.4	3.2	0.0	17.0
1	Control	223	3.3	3.3	0.0	16.0	3.7
1	Intervention	234	3.2	3.1	0.0	18.0	3.5	−0.2	−0.7	0.2	0.3381	0.4166
12	Control	204	2.9	3.0	0.0	16.0	3.5
12	Intervention	212	2.8	3.2	0.0	18.0	3.2	−0.3	−0.7	0.2	0.2436	0.1576
Quality of life
0	Control	268	76.5	13.6	23.4	124.8
0	Intervention	268	77.1	12.2	27.7	115.6
1	Control	221	77.5	15.9	11.4	124.8	78.1
1	Intervention	234	79.6	14.2	31.2	124.8	79.3	1.2	−0.9	3.2	0.2562	0.1915
12	Control	203	77.2	14.5	20.6	124.8	78.1
12	Intervention	213	79.1	15.1	27.0	124.8	78.8	0.7	−1.4	2.8	0.5111	0.5923

AQoL, Assessment of Quality of Life; CL, confidence limit; HADS, Hospital Anxiety and Depression Scale; LS, least square; Max, maximum; Min, minimum.