Table 3

Analysis of secondary outcomes measured at 6 months

 Secondary outcomes Primary care (n=149) Sleep unit (n=153) Difference in the mean change adjusted for baseline (ITT)* P values Mean (95% CI) Mean (95% CI) Mean (95% CI) BMI (kg/m2) Baseline 31.01 (30.20 to 31.82) 31.75 (30.71 to 32.78) – – 6 months 30.59 (29.76 to 31.44) 30.87 (29.92 to 31.81) – – Change −0.41 (−0.90 to 0.07) −0.87 (−0.58 to −0.17) −0.13 (−0.57 to 0.31) 0.547 SBP (mm Hg) Baseline 135.04 (131.89 to 138.19) 136.5 (133.23 to 139.76) – – 6 months 134.29 (131.77 to 136.81) 133.59 (130.25 to 136.92) – – Change −0.75 (−3.34 to 1.83) −2.90 (−5.81 to 0.001) −0.05 (−3.31 to 3.41) 0.978 DBP (mm Hg) Baseline 81.24 (79.40 to 83.08) 86.25 (84.28 to 88.23) – – 6 months 81.67 (78.96 to 82.37) 85.85 (82.01 to 85.68) – – Change −0.57 (−2.26 to 1.12) −2.40 (−4.31 to −0.49)‡ −1.99 (−4.55 to 0.56) 0.125 Patient satisfaction†§ 6 months 92.82 (90.97 to 94.68) 95.64 (94.31 to 96.97) −2.71 (−4.96 to 0.55) 0.018 Compliance with CPAP (hours/night)§ n=70 n=58 6 months 5.30 (4.83 to 5.75) 5.35 (3.95 to 6.75) 0.24 (−0.63 to 1.12) 0.586
• Change computed as the difference between the 6 month values and the baseline values. In the descriptive analysis, the imputed values were represented by the mean of the values imputed for each patient. The difference in the mean change is computed as the difference in PC values compared with SU values. Statistically significant p values (<0.05) are shown in bold.

• *Multiple imputations were used.

• †Patient satisfaction visual analogue scale (range from 0 to 100).

• ‡P<0.001 for a paired comparison of outcome measures examining the change from baseline to 6 months.