Analysis of secondary outcomes measured at 6 months
| Secondary outcomes | Primary care (n=149) | Sleep unit (n=153) | Difference in the mean change adjusted for baseline (ITT)* | P values |
| Mean (95% CI) | Mean (95% CI) | Mean (95% CI) | ||
| BMI (kg/m2) | ||||
| Baseline | 31.01 (30.20 to 31.82) | 31.75 (30.71 to 32.78) | – | – |
| 6 months | 30.59 (29.76 to 31.44) | 30.87 (29.92 to 31.81) | – | – |
| Change | −0.41 (−0.90 to 0.07) | −0.87 (−0.58 to −0.17) | −0.13 (−0.57 to 0.31) | 0.547 |
| SBP (mm Hg) | ||||
| Baseline | 135.04 (131.89 to 138.19) | 136.5 (133.23 to 139.76) | – | – |
| 6 months | 134.29 (131.77 to 136.81) | 133.59 (130.25 to 136.92) | – | – |
| Change | −0.75 (−3.34 to 1.83) | −2.90 (−5.81 to 0.001) | −0.05 (−3.31 to 3.41) | 0.978 |
| DBP (mm Hg) | ||||
| Baseline | 81.24 (79.40 to 83.08) | 86.25 (84.28 to 88.23) | – | – |
| 6 months | 81.67 (78.96 to 82.37) | 85.85 (82.01 to 85.68) | – | – |
| Change | −0.57 (−2.26 to 1.12) | −2.40 (−4.31 to −0.49)‡ | −1.99 (−4.55 to 0.56) | 0.125 |
| Patient satisfaction†§ | ||||
| 6 months | 92.82 (90.97 to 94.68) | 95.64 (94.31 to 96.97) | −2.71 (−4.96 to 0.55) | 0.018 |
| Compliance with CPAP (hours/night)§ | n=70 | n=58 | ||
| 6 months | 5.30 (4.83 to 5.75) | 5.35 (3.95 to 6.75) | 0.24 (−0.63 to 1.12) | 0.586 |
Change computed as the difference between the 6 month values and the baseline values. In the descriptive analysis, the imputed values were represented by the mean of the values imputed for each patient. The difference in the mean change is computed as the difference in PC values compared with SU values. Statistically significant p values (<0.05) are shown in bold.
*Multiple imputations were used.
†Patient satisfaction visual analogue scale (range from 0 to 100).
‡P<0.001 for a paired comparison of outcome measures examining the change from baseline to 6 months.
§Not adjusted for baseline.
BMI, Body Mass Index; DBP, diastolic blood pressure; HUI, Health Utility Index; ITT, intention-to-treat analysis; SBP, systolic blood pressure.