Table 1

Clinical characteristics of children exposed or not exposed to passive smoking

Children exposed to passive smokingChildren not exposed to passive smokingP
N5757
Age (years)8.7 (7.8 to 9.5)8.7 (8.0 to 9.4)0.949
Females/males26/3126/311.0
Systolic blood pressure, mm Hg115 (112 to 118)112 (109 to 115)0.198
Diastolic blood pressure, mm Hg75 (71 to 78)70 (68 to 73)0.60
Parents cigarettes/day, No.12 (11 to 14) <0.001
Serum cotinine (ng/mL)35.7 (33 to 38)1.5 (1.2 to 1.8) <0.001
Body mass index18 (17 to 19)17 (16 to 18)0.157
Total cholesterol level, mg/dL169 (162 to 175)160 (155 to 166)0.052
Fasting glucose level, mg/dL88 (84 to 91)87 (83 to 89)0.617
sNOX-2dp (pg/mL)26 (24 to 29)18 (16 to 20) <0.001
8-iso-PGF2α (pmol/L)169 (142 to 185)150 (130 to 159) <0.001
NO bioavailability (µM)51 (48 to 54)59 (55 to 62) <0.001
FMD (%)6.1 (4 to 9.1)7.7 (5.1 to 10) 0.006
IMT (mm)0.50 (0.48 to 0.52)0.49 (0.46 to 0.51)0.502
  • Data are reported as mean and 95% CI. Italicised values show a  P value statistically significant.

  • FMD, flow-mediated dilation; IMT, intimal-medial thickening; NO, nitric oxide; sNOX-2dp, soluble Nox2.