Changes in respiratory muscle function
| Variables | Intervention group | Control group | Adjusted difference (95% CI) at post training | P values* | ||
| Pre training | Post training | Pre training | Post training | |||
| PImax (cm H2O) | 53 (14) | 75 (19)† | 52 (11) | 61 (13)† | 14 (10 to 18) | <0.001 |
| PEmax (cm H2O) | 110 (40) | 127 (52)† | 104 (30) | 117 (35)† | 3 (−7 to 14) | 0.531 |
| Endurance breathing (s) | 240 (108) | 593 (270)† | 251 (96) | 413 (236)† | 189 (114 to 265) | <0.001 |
| Ti/Ttot (%) | 31 (17) | 21 (14)† | 34 (19) | 28 (17)† | −5.6 (−9.3 to −1.9) | 0.003 |
| Total work (J) | 78 (83) | 258 (153)† | 79 (97) | 159 (162)† | 100 (57 to 142) | <0.001 |
| Average power (W) | 1.8 (1.4) | 3.1 (1.7)† | 1.5 (1.5) | 2.1 (1.6)† | 0.8 (0.4 to 1.1) | <0.001 |
Data are presented as mean (SD) and mean (95% CI).Analyses are based on 174 (PImax, 100% of completers) patients.
*P values are reported for between-group comparisons (analysis of covariance of post-training values adjusted for baseline values as covariates).
†A statistically significant within-group difference (p<0.05).
PEmax, maximal expiratory mouth pressure; PImax , maximal inspiratory mouth pressure; Ti/Ttot, inspiratory duty cycle.