Clinical characteristics | Included conservative fluid arm (n=82) | Included liberal fluid arm (n=92) | P values* | Not included (n=826) |
Age | 48 (39, 59) | 44 (35, 60) | 0.70 | 49 (39, 61) |
Male | 44 (54%) | 42 (46%) | 0.29 | 448 (54%) |
Caucasian | 64 (79%) | 62 (68%) | 0.05 | 513 (62%) |
BMI (kg/m2) | 28 (25, 34) | 28 (23, 34) | 0.59 | 27 (23, 32) |
APACHE III | 89 (74, 105) | 95 (81, 121) | 0.07 | 91 (69, 117) |
60-day mortality | 18 (22%) | 26 (28%) | 0.34 | 225 (27%) |
RALE baseline | 28 (17, 35) | 26 (20, 34) | 0.64 | NA |
RALE day 3 | 16 (10, 23) | 25 (16, 35) | <0.001 | NA |
Change in RALE† | −8 (−1, –16) | −1 (−8, 5) | <0.001 | NA |
Data as median and IQR.
↵*P value is for comparison between patients in the conservative and liberal fluid management arms who were included in the current study.
†Change in RALE from baseline radiograph to day 3 radiograph. Negative number indicates that the score decreased from baseline to day 3.
APACHE III, acute physiology and chronic health evaluation III; BMI, body mass index; NA, not available; RALE, radiographic assessment of lung oedema.