Thresholds for weighting risk factors
| Description | Thresholds and criteria for decision | |
| Risk weighting (OR) | Greatly increased risk | Majority of ORs >2.5 |
| Moderately increased risk | Majority of ORs 1.5–2.5 | |
| Slightly increased risk | Majority of ORs 1.1–1.5 | |
| No effect | Majority of ORs <1.1 | |
| Confidence | Highly confident | Number, design and quality of studies, consistency of results, biological plausibility of factors |
| Moderately confident | ||
| Slightly confident | ||
| Inconclusive | Unable to decide on risk | Inconsistent or insufficient evidence |