Table 4

The average number of latent TB infection (LTBI) treatments needed to prevent one incident TB by result of QuantiFERON TB Gold (n=44 875)

No LTBI treatmentLTBI treatmentNNT (95% CI)
nTBnTB
Total study population42 43325724424
  Positive, total*77472192131438 (35 to 41)
   Low positive1809173570106 (102 to 112)
   Medium positive208446586359 (44 to 90)
   High positive38541561188125 (24 to 27)
Negative33 8353329301025 (1014 to 1036)
Inconclusive8515180170 (159 to 182)
Foreign-born, total
  Positive, total*65801641726434 (32 to 38)
   Low positive125213222078 (74 to 83)
   Medium positive173536441354 (38 to 92)
   High positive35931151063125 (24 to 27)
Negative10 760141110598 (587 to 609)
Inconclusive229512046 (41 to 53)
Norwegian-born, total
  Positive, total*116712405090 (85 to 95)
   Low positive55711350557 (514 to 607)
   Medium positive34921450175 (158 to 195)
   High positive2619125026 (23 to 30)
Negative23 0751018201538 (1519 to 1558)
Inconclusive622060
  • *Low positive, IFN-γ 0.35 to <1.0; medium positive, IFN-γ 1.0 to <4.0; high positive, IFN-γ>4.0 IU/mL.

  • IFN-γ , interferon-γ; NNT, numbers needed to treat.