C) Chemotherapy
Geographical quintile of chemotherapy		Adjusted for age and sex		Adjusted for Age and sex and restricted to Stage IV patients
		HR	95% CI	HR	95% CI
1	Lowest	1.00		1.00
2		0.96	0.94 to 0.98	0.97	0.94 to 0.99
3		0.90	0.89 to 0.92	0.94	0.91 to 0.96
4		0.90	0.88 to 0.92	0.92	0.89 to 0.94
5	Highest	0.90	0.88 to 0.91	0.90	0.87 to 0.92
χ2(one df)		138.5		73.8
P for trend		<0.001		<0.001