Latent class analysis of subjects enrolled in ARMA at day 3 and not assigned to active drug in the ketoconazole or lisofylline substudies
| N Classes | BIC | Entropy | Number assigned to each subphenotype | P value* | |||
| Class 1, n (%) | Class 2, n (%) | Class 3, n (%) | Class 4, n (%) | ||||
| 1 | 22 106 | 343 | |||||
| 2 | 21 552 | 0.87 | 247 (72) | 96 (28) | <0.0001 | ||
| 3 | 21 516 | 0.91 | 240 (70) | 62 (18) | 41 (12) | 0.33 | |
| 4 | 21 523 | 0.84 | 162 (47) | 92 (27) | 49 (14) | 40 (12) | 0.23 |
*P value represents the Vuong-Lo-Mendell-Rubin (VLMR) test, which tests if k classes confer an improved model fit over k-1 classes.
Entropy, an index ranging between 0 and 1, which indicates separation of classes.
BIC, Bayesian information criteria, a measure of model fit.