Cluster (n) | Cluster label | Median AHI* (events/hour) | Conventional OSA severity* |
A (533) | Mild | 4 | None/mild |
B (119) | PLMS | 10 | |
C (186) | NREM and poor sleep | 19 | Moderate |
D (168) | REM and hypoxia | 19 | |
E (75) | Hypopnoea and hypoxia | 44 | Severe |
F (42) | Arousal and poor sleep | 68 | |
G (124) | Combined severe | 84 |
*OSA severity definitions: none/mild (AHI <15), moderate (15≤ AHI<30) and severe (AHI ≥30). AHI was not used in generating patient clusters. Median AHIs and severity categories based on median AHI for each cluster are shown for descriptive purposes only (mean AHIs were 7.5, 13.6, 24.0, 25.0, 47.6, 72.6 and 82.4 for clusters A, B, C, D, E, F and G, respectively).
AHI,apnoea–hypopnoea index; NREM, non-rapid eye movement; OSA, obstructive sleep apnoea; PLMS, periodic limb movements of sleep; REM, rapid eye movement.