Table 2

Side effects experienced while taking rapamycin according to duration of treatment and categorised by the Common Terminology Criteria for Adverse Events

% affected
Treatment duration (months)1612LatestEver
Common Terminology Criteria for Adverse Events Category
Gastrointestinal
Oral mucositis
Diarrhoea
Nausea
Abdominal pain
Indigestion
Bloating
Reflux symptoms
58
32
24
6
6
0
0
35
12
3
0
0
3
0
24
10
5
0
0
5
0
13
0
0
0
0
6
5
65
41
24
6
6
9
5
Dermatological
Acne
Rash
Dry skin
6
3
6
17
10
0
18
0
0
0
0
0
41
12
6
Soft tissues
Peripheral oedema
57009
Sexual or reproductive function
Menstrual cycle disturbances
075015
Constitutional symptoms
Fatigue
37059
Infection
Upper respiratory/bronchitis
Tonsillitis
Pneumonia
Urinary tract infection
Skin infection
12
3
0
0
3
24
7
3
7
7
10
0
0
0
0
13
0
5
0
0
35
6
5
6
9
Musculoskeletal
Arthralgia or myalgia
33506