Table 2

Summary of exacerbations and presumed bacterial LRTIs for each cohort

Under 5s5 to 17s18 to 54s55+
Patients (%)Rate per
10 person-years (95% CI)
Patients (%)Rate per
10 person-years
(95% CI)
Patients (%)Rate per
10 person-years
(95% CI)
Patients (%)Rate per
10 person-years
(95% CI)
Total cohort17 32082 707210 724113 575
Exacerbations75744.27 (4.18 to 4.38)39 9701.48 (1.47 to 1.50)245 0773.22 (3.21 to 3.24)435 0299.40 (9.37 to 9.42)
Patients who exacerbated3706 (21.4*)18 449 (22.3*)80 041 (38*)70 954 (62.5*)
Annual exacerbation frequency
 ≤0.555312 43347 58829 620
 0.5–11131360017 42316 439
 1.1–31577204712 15617 569
 3.1–636929221214419
 >676777532907
Level of care
 GP only521126 543155 054334 850
 A&E2329842257561
 Hospitalisation (<1 day)966651546 22750 385
 Hospitalisation (≥1 day)1165592541 50249 015
 Died<5<537218
Antibiotic-treated LRTIs21790.61 (0.58 to 0.64)11 4880.22 (0.21 to 0.22)81 0840.71 (0.71 to 0.72)171 3521.93 (1.92 to 1.94)
Patients with Ax-LRTI1612 (9.3*)8252 (10*)41 874 (19.9*)34 656 (30.5*)
  • *Per cent of total cohort, ; annual frequency is the number of patients who exacerbated within each band of annual frequency.

  • A&E, Accident & Emergency; Ax-LRTI, antibiotic-treated lower respiratory tract infection; GP, general practitioner; LRTI, lower respiratory tract infection.