Table 1

Main clinical, physiological and HRCT characteristics in patients separated according to <10% (n=77) and ≥10% predicted FVC (n=35) after 6–12-month period

Finding<10% FVC
(n=77)
≥10% FVC
(n=35)
p Value
Age, years57.3±13.061.1±13.70.16
Female sex, n (%)55 (71.4)23 (74.3)0.37
Weight loss, n (%)26 (33.8)9 (25.7)0.88
Dyspnoea, n (%)69 (89.6)29 (82.9)0.32
Fine crackles, n (%)61 (79.2)29 (82.9)0.65
Clubbing, n (%)10 (13.0)11 (31.4)0.55
Inspiratory squeaks, n (%)11 (14.3)4 (11.4)0.68
FVC % predicted, mean ± SD66.1±18.672.6±17.90.09
FEV1/FVC0.86±0.070.86±0.080.89
SpO2, rest, mean ± SD (n=103)93.9±4.292.9±4.40.28
Reticular pattern, n (%)51 (66)24 (68)0.71
Ground-glass opacities, n (%)41 (53)22 (62)0.34
Mosaic, n (%)34 (44)16 (45)0.87
Honeycombing, n (%)26 (33)10 (28)0.58
Centrilobular nodules, n (%)17 (22)6 (17)0.54
Vertical distribution—diffuse/upper lobes/lower lobes, n21/22/339/10/140.99
Axial distribution—central, peripheral, both, n9/23/449/9/210.62