Table 12

Summary sensitivities and specificities for Fibulin-3

		Sensitivity	Specificity	Area under the curve	Cut-off (ng/mL)
Pass et al²³⁰	Plasma	100	100	1	33^*
	Plasma	95	96	0.99	53^†
	Pleural fluid	84	92	0.93	346
Agha et al²³¹	Serum	88	81.8	0.776	67
	Pleural fluid	72	80	0.878	150
Elgazzar et al²³²	Serum	100	97	0.98	54
	Pleural fluid	90	97	0.94	520
Creaney et al²³³	Plasma	22	95	n/a	52
	Plasma	48	71	0.671	29
	Pleural fluid	59	52	0.588	346
Kirschner et al⁶¹	Plasma	14	97		29^‡
		13	88^§

* Detroit cohort.
† New York cohort.
‡ Sydney cohort.
§ Vienna cohort.